ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04630
Name Jak-STAT signaling pathway
No. of Genes in ADHDgene  25
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 25)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
CNTF ciliary neurotrophic factor 11q12 1(1/0/0)
IL20RA interleukin 20 receptor, alpha 6q23.3 1(0/0/1)
CNTFR ciliary neurotrophic factor receptor 9p13 1(1/0/0)

Genes from other sources Help(count: 22)

Approved Symbol Approved Name Location Source
IL5RA interleukin 5 receptor, alpha 3p26-p24 Mapped by CNV
LIFR leukemia inhibitory factor receptor alpha 5p13-p12 Mapped by significant region
SOCS1 suppressor of cytokine signaling 1 16p13.13 Mapped by significant region
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 11q23.3 Mapped by significant region
PRLR prolactin receptor 5p14-p13 Mapped by significant region
IRF9 interferon regulatory factor 9 14q11.2 Mapped by significant region
GHR growth hormone receptor 5p14-p12 Mapped by CNV; Mapped by significant region
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 Mapped by significant region
CCND1 cyclin D1 11q13 Mapped by significant region
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 5q31.1-q33.1 Mapped by significant region
OSMR oncostatin M receptor 5p13.2 Mapped by significant region
CCND3 cyclin D3 6p21 Mapped by CNV
IL6 interleukin 6 (interferon, beta 2) 7p21-p15 Mapped by significant region
IL22RA2 interleukin 22 receptor, alpha 2 6q24.1-q24.2 Mapped by significant region
IL7R interleukin 7 receptor 5p13 Mapped by significant region
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 Mapped by CNV
CLCF1 cardiotrophin-like cytokine factor 1 11q13.3 Mapped by significant region
IL11RA interleukin 11 receptor, alpha 9p13 Mapped by LD-proxy
CREBBP CREB binding protein 16p13.3 Mapped by significant region
IL10RA interleukin 10 receptor, alpha 11q23 Mapped by significant region
IFNGR1 interferon gamma receptor 1 6q23-q24 Mapped by significant region
CTF1 cardiotrophin 1 16p11.2 Mapped by CNV