ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa00230
Name Purine metabolism
No. of Genes in ADHDgene  27
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 27)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
FHIT fragile histidine triad 3p14.2 1(0/0/1)
NT5C2 5'-nucleotidase, cytosolic II 10q24.32 1(1/0/0)

Genes from other sources Help(count: 25)

Approved Symbol Approved Name Location Source
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 16p13.3 Mapped by significant region
NME4 NME/NM23 nucleoside diphosphate kinase 4 16p13.3 Mapped by significant region
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 20p Mapped by CNV
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 11q21-q22 Mapped by significant region
ADK adenosine kinase 10q22.2 Mapped by LD-proxy
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 11q13 Mapped by significant region
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 6q22-q23 Mapped by significant region
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 11q14 Mapped by significant region
RRM2 ribonucleotide reductase M2 2p25-p24 Mapped by significant region
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 6q22 Mapped by significant region
NT5M 5',3'-nucleotidase, mitochondrial 17p11.2 Mapped by significant region
POLR1A polymerase (RNA) I polypeptide A, 194kDa 2p11.2 Mapped by CNV
GMPR2 guanosine monophosphate reductase 2 14q11.2 Mapped by significant region
ADCY4 adenylate cyclase 4 14q11.2 Mapped by significant region
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2q35 Mapped by significant region
ADCY2 adenylate cyclase 2 (brain) 5p15.3 Mapped by significant region
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 11q13 Mapped by significant region
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 11q13.1 Mapped by significant region
ADCY3 adenylate cyclase 3 2p23.3 Mapped by LD-proxy
PDE7B phosphodiesterase 7B 6q23-q24 Mapped by significant region
APRT adenine phosphoribosyltransferase 16q24 Mapped by significant region
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 9q33 Mapped by significant region
PDE4D phosphodiesterase 4D, cAMP-specific 5q12 Mapped by CNV
ADCY9 adenylate cyclase 9 16p13.3 Mapped by significant region
PDE2A phosphodiesterase 2A, cGMP-stimulated 11q13.1-q14.1 Mapped by significant region