ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04012
Name ErbB signaling pathway
No. of Genes in ADHDgene  20
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 20)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
EREG epiregulin 4q21.21 1(0/0/1)
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0)

Genes from other sources Help(count: 18)

Approved Symbol Approved Name Location Source
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
CAMK2D calcium/calmodulin-dependent protein kinase II delta 4q26 Mapped by CNV
MAPK9 mitogen-activated protein kinase 9 5q35 Mapped by CNV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 11q23.3 Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 22q11.21 Mapped by CNV
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 11q13.1 Mapped by significant region
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 16q24.1 Mapped by significant region
BTC betacellulin 4q13.3 Mapped by CNV
BAD BCL2-associated agonist of cell death 11q13.1 Mapped by significant region
NCK2 NCK adaptor protein 2 2q12 Mapped by PBA pathway
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 17q11.2-q12 Mapped by LD-proxy
NCK1 NCK adaptor protein 1 3q21 Mapped by PBA pathway
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 Mapped by CNV
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 11q13-q14 Mapped by significant region
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 9q22.1 Mapped by significant region
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 Mapped by significant region
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 20p12 Mapped by CNV