ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Other Variant Report

Basic Info
Name SLC6A2_promoter_-3081A/T
Type point mutation
Location promoter
Related Gene SLC6A2
No. of Study 3 (significant: 2; non-significant 1; trend: 0)

Variant related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Joung Y, 2010 A/T logistic regression P-value=0.02, X2=5.60 in the ...... logistic regression P-value=0.02, X2=5.60 in the allele frequencies, OR=1.59 for T allele; logistic regression P-value=0.02, X2=7.1 in the genotype frequencies, OR=4.57 for TT and OR=1.96 for AT More... provided further evidence of association provided further evidence of association Significant
Kim CH, 2006 frequency of -3081(T) allele, P-value=0.008, OR=2.00, X...... frequency of -3081(T) allele, P-value=0.008, OR=2.00, X2=7.07; logistic regression results for the linear trend contrasting the number of T alleles: P-value=0.011, R2=0.06, X2=6.49 More... a significant association was observed a significant association was observed Significant
Cho SC, 2008 A/T allelic TDT P-value=0.160, genotypic TDT P-value=0.339 allelic TDT P-value=0.160, genotypic TDT P-value=0.339 there was no evidence for biased transmission of any of the ...... there was no evidence for biased transmission of any of the alleles More... Non-significant