ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005923
Name tight junction
Type cellular component
No. of Genes in ADHDgene  18
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 18)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 7q21 1(0/0/1) IDA[10760291]
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10q21 2(0/2/0) IDA[14757759]
LIN7C lin-7 homolog C (C. elegans) 11p14 1(1/0/0) IEA

Genes from other sources Help (count: 15)

Approved Symbol Approved Name Source Evidence[PMID]
TJP1 tight junction protein 1 Mapped by CNV; Mapped by significant region IDA[14757759]
APC adenomatous polyposis coli Mapped by LD-proxy; Mapped by PBA pathway IDA[18502210]
CLDN9 claudin 9 Mapped by significant region ISS
CLDN25 claudin 25 Mapped by significant region IEA
AMICA1 adhesion molecule, interacts with CXADR antigen 1 Mapped by significant region IDA[15800062]
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 Mapped by PBA pathway IEA
CLDN5 claudin 5 Mapped by CNV ISS
AMOTL1 angiomotin like 1 Mapped by significant region IDA[16019084]
CLMP CXADR-like membrane protein Mapped by significant region IEA
JAM3 junctional adhesion molecule 3 Mapped by significant region IEA
CLDN6 claudin 6 Mapped by significant region ISS
ESAM endothelial cell adhesion molecule Mapped by significant region IEA
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region IDA[15761148]
CCND1 cyclin D1 Mapped by significant region IEA
UBN1 ubinuclein 1 Mapped by significant region ISS