ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0004867
Name serine-type endopeptidase inhibitor activity
Type molecular function
No. of Genes in ADHDgene  14
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 14)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 3p21.1 1(1/0/0) IEA
FURIN furin (paired basic amino acid cleaving enzyme) 15q26.1 1(0/0/1) IDA[10567353]

Genes from other sources Help (count: 12)

Approved Symbol Approved Name Source Evidence[PMID]
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 Mapped by LD-proxy IEA
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) Mapped by significant region IBA
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 Mapped by significant region IDA[11527969]
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 Mapped by LD-proxy IEA
WFDC1 WAP four-disulfide core domain 1 Mapped by CNV; Mapped by significant region IEA
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 Mapped by CNV IBA
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 Mapped by CNV IBA
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 Mapped by CNV IBA
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 Mapped by significant region IBA; NAS[12878203]
AMBP alpha-1-microglobulin/bikunin precursor Mapped by significant region TAS[12817471]
APLP2 amyloid beta (A4) precursor-like protein 2 Mapped by significant region IEA
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 Mapped by significant region IEA