ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0042220
Name response to cocaine
Type biological process
No. of Genes in ADHDgene  11
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 11)

Literature-origin genes (count: 9)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3p25.3 1(0/1/0) IEA
OXTR oxytocin receptor 3p25 1(0/1/0) IEA
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 10q25 2(0/2/0) IEA
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 6q13 14(5/9/0) IEA
DRD5 dopamine receptor D5 4p16.1 22(14/6/2) IEA
DRD3 dopamine receptor D3 3q13.3 8(1/7/0) IEP[10415668]
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 70(43/26/1) IEA
CNR1 cannabinoid receptor 1 (brain) 6q14-q15 1(1/0/0) IEA
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) ISS

Genes from other sources Help (count: 2)

Approved Symbol Approved Name Source Evidence[PMID]
TACR3 tachykinin receptor 3 Mapped by CNV IEA
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal Mapped by CNV; Mapped by PBA pathway IEA