ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006974
Name response to DNA damage stimulus
Type biological process
No. of Genes in ADHDgene  41
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 41)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FANCL Fanconi anemia, complementation group L 2p16.1 1(0/1/0) IMP[16916645]
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 2p23 1(1/0/0) IEP[7826398]

Genes from other sources Help (count: 39)

Approved Symbol Approved Name Source Evidence[PMID]
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 Mapped by significant region IDA
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway IDA[17500065]
ATMIN ATM interactor Mapped by significant region IEA
APC adenomatous polyposis coli Mapped by LD-proxy; Mapped by PBA pathway IDA[14728717]
AATF apoptosis antagonizing transcription factor Mapped by CNV IEP[18049476]
RPS3 ribosomal protein S3 Mapped by significant region IEP[17560175]
CHEK1 checkpoint kinase 1 Mapped by significant region IMP
RAD1 RAD1 homolog (S. pombe) Mapped by significant region TAS[9872989]
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) Mapped by PBA pathway IMP
MCM9 minichromosome maintenance complex component 9 Mapped by significant region IDA
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 Mapped by significant region IEA
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 Mapped by significant region IDA
TAOK2 TAO kinase 2 Mapped by CNV IDA[17396146]
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Mapped by CNV IDA[18468999]
CCND1 cyclin D1 Mapped by significant region IDA[19412162]
STK11 serine/threonine kinase 11 Mapped by CNV IEA
RNF169 ring finger protein 169 Mapped by significant region IDA; IMP
FBXO31 F-box protein 31 Mapped by significant region IDA[19412162]
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region IMP[15790808]
EGLN3 egl-9 family hypoxia-inducible factor 3 Mapped by Literature SNP IEA
NIPBL Nipped-B homolog (Drosophila) Mapped by significant region IMP[17468178]
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV IEA
ERCC8 excision repair cross-complementing rodent repair deficiency, complementation group 8 Mapped by CNV IDA[11782547]
ATAD5 ATPase family, AAA domain containing 5 Mapped by CNV IEA
IRF7 interferon regulatory factor 7 Mapped by LD-proxy TAS[16979567]
INIP INTS3 and NABP interacting protein Mapped by significant region IMP[19683501]
TP53BP1 tumor protein p53 binding protein 1 Mapped by Literature SNP IDA[17500065]
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IEA
CHD1L chromodomain helicase DNA binding protein 1-like Mapped by CNV IDA[19661379]
BARD1 BRCA1 associated RING domain 1 Mapped by significant region NAS[15905410]
TRIP12 thyroid hormone receptor interactor 12 Mapped by PBA pathway IMP
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region IDA[9872989]
MEN1 multiple endocrine neoplasia I Mapped by significant region IDA[16690369]
SGK1 serum/glucocorticoid regulated kinase 1 Mapped by significant region IEA
USP28 ubiquitin specific peptidase 28 Mapped by significant region IDA[17873522]
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region IDA[17500065]
H2AFX H2A histone family, member X Mapped by significant region IDA[15149599]
YAP1 Yes-associated protein 1 Mapped by significant region IDA[18280240]
ALKBH8 alkB, alkylation repair homolog 8 (E. coli) Mapped by significant region IDA