ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0014069
Name postsynaptic density
Type cellular component
No. of Genes in ADHDgene  26
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 26)

Literature-origin genes (count: 12)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0) IEA
LIN7C lin-7 homolog C (C. elegans) 11p14 1(1/0/0) IEA
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IEA
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 12p13.3 3(0/3/0) IDA[14140941]
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) IEA
GRM5 glutamate receptor, metabotropic 5 11q14.3 2(1/0/1) IEA
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 4(1/3/0) IEA
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 15q24 1(0/1/0) ISS
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12p12 2(1/1/0) IEA
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 7q21 1(0/0/1) ISS
DISC1 disrupted in schizophrenia 1 1q42.1 1(1/0/0) IEA
GRM1 glutamate receptor, metabotropic 1 6q24 1(1/0/0) IEA

Genes from other sources Help (count: 14)

Approved Symbol Approved Name Source Evidence[PMID]
P2RX6 purinergic receptor P2X, ligand-gated ion channel, 6 Mapped by CNV IEA
AXIN1 axin 1 Mapped by significant region IBA
GOPC golgi-associated PDZ and coiled-coil motif containing Mapped by significant region IEA
SHANK2 SH3 and multiple ankyrin repeat domains 2 Mapped by significant region IEA
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region IEA
PSD3 pleckstrin and Sec7 domain containing 3 Mapped by Literature SNP IEA
MTMR2 myotubularin related protein 2 Mapped by significant region ISS
NLGN1 neuroligin 1 Mapped by CNV TAS[15797875]
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 Mapped by PBA pathway ISS
ARHGAP32 Rho GTPase activating protein 32 Mapped by significant region IEA
ADORA2A adenosine A2a receptor Mapped by CNV IEA
CNIH2 cornichon family AMPA receptor auxiliary protein 2 Mapped by significant region ISS
CHRM1 cholinergic receptor, muscarinic 1 Mapped by significant region; Mapped by PBA pathway IEA
DLG2 discs, large homolog 2 (Drosophila) Mapped by significant region IEA