ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0045893
Name positive regulation of transcription, DNA-dependent
Type biological process
No. of Genes in ADHDgene  89
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 89)

Literature-origin genes (count: 10)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MAP2K3 mitogen-activated protein kinase kinase 3 17q11.2 1(0/1/0) IDA[11980910]
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 6p21.1-p12.3 1(0/0/1) NAS[9787080]
HAS3 hyaluronan synthase 3 16q22.1 1(0/0/1) IDA[16900089]
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0) IDA[17500053]
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2p25 1(0/1/0) ISS
NPAS3 neuronal PAS domain protein 3 14q13.1 1(1/0/0) ISS
ETV5 ets variant 5 3q28 1(1/0/0) IEA
ZNF423 zinc finger protein 423 16q12 1(0/0/1) IDA[10660046]
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) IDA[11505339]; IMP[16373396]
CREB5 cAMP responsive element binding protein 5 7p15 1(0/0/1) IDA[8378084]

Genes from other sources Help (count: 79)

Approved Symbol Approved Name Source Evidence[PMID]
KAT5 K(lysine) acetyltransferase 5 Mapped by significant region IDA[14966270]; NAS[15572661]
RSF1 remodeling and spacing factor 1 Mapped by significant region IDA[11788598]
FOXE1 forkhead box E1 (thyroid transcription factor 2) Mapped by significant region IDA[9697705]
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) Mapped by PBA pathway IMP[11279242]
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) Mapped by significant region IMP[12805222]
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Mapped by CNV IDA[19343227]
MYB v-myb avian myeloblastosis viral oncogene homolog Mapped by significant region IMP; NAS[2189102]
HINFP histone H4 transcription factor Mapped by significant region IDA[17163457]
CIITA class II, major histocompatibility complex, transactivator Mapped by significant region IDA[19041327]
ANKRD49 ankyrin repeat domain 49 Mapped by significant region IDA[11162141]
CREBBP CREB binding protein Mapped by significant region IDA[11742995]; ISS
RREB1 ras responsive element binding protein 1 Mapped by CNV TAS[9305772]
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy IEA
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region IDA[19282672]
MED17 mediator complex subunit 17 Mapped by significant region; Mapped by PBA pathway IDA[10198638]
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 Mapped by PBA pathway IDA[14701856]
HMGA1 high mobility group AT-hook 1 Mapped by PBA pathway IMP[10428834]
NSD1 nuclear receptor binding SET domain protein 1 Mapped by PBA pathway IDA[11509567]
ZNF287 zinc finger protein 287 Mapped by significant region IEA
TBX1 T-box 1 Mapped by CNV IDA[17273972]; ISS
MAPK9 mitogen-activated protein kinase 9 Mapped by CNV IEA
FZD4 frizzled class receptor 4 Mapped by significant region IDA[17955262]
CRLF3 cytokine receptor-like factor 3 Mapped by CNV IDA[19427400]
HNF1B HNF1 homeobox B Mapped by CNV IDA
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 Mapped by LD-proxy IEA
FEV FEV (ETS oncogene family) Mapped by significant region IEA
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway TAS[12519782]
THRAP3 thyroid hormone receptor associated protein 3 Mapped by PBA pathway IDA[10198638]
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IDA[7749983]
EBF1 early B-cell factor 1 Mapped by significant region IEA
TGFB1I1 transforming growth factor beta 1 induced transcript 1 Mapped by PBA pathway IDA[10075738]; NAS[15572661]
ROR2 receptor tyrosine kinase-like orphan receptor 2 Mapped by significant region IEA
NRIP1 nuclear receptor interacting protein 1 Mapped by PBA pathway NAS[15572661]
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 Mapped by significant region IDA[11909962]
RFX6 regulatory factor X, 6 Mapped by significant region IDA
SPI1 spleen focus forming virus (SFFV) proviral integration oncogene Mapped by LD-proxy IDA[12833137]
MED13 mediator complex subunit 13 Mapped by PBA pathway IDA[10198638]
MYRF myelin regulatory factor Mapped by LD-proxy; Mapped by significant region ISS
ZBTB16 zinc finger and BTB domain containing 16 Mapped by significant region IDA
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta Mapped by PBA pathway IDA[15790729]
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) Mapped by significant region IMP[12663744]
SOX8 SRY (sex determining region Y)-box 8 Mapped by significant region ISS
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IDA[10198638]
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) Mapped by CNV; Mapped by significant region IEA
RNF20 ring finger protein 20, E3 ubiquitin protein ligase Mapped by significant region IMP[16713563]
KMT2A lysine (K)-specific methyltransferase 2A Mapped by significant region IMP[15960975]
WNT6 wingless-type MMTV integration site family, member 6 Mapped by significant region IEA
LHX1 LIM homeobox 1 Mapped by CNV ISS
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region IDA[9389648]
PICALM phosphatidylinositol binding clathrin assembly protein Mapped by significant region IDA[11425879]
ILK integrin-linked kinase Mapped by CNV IMP
RAN RAN, member RAS oncogene family Mapped by PBA pathway NAS[15572661]
LRP5 low density lipoprotein receptor-related protein 5 Mapped by CNV; Mapped by significant region IDA[17955262]
IRF8 interferon regulatory factor 8 Mapped by significant region IEA
LHX2 LIM homeobox 2 Mapped by significant region ISS
MED16 mediator complex subunit 16 Mapped by PBA pathway IDA[10198638]
USP22 ubiquitin specific peptidase 22 Mapped by significant region IMP[18206973]
TP53BP1 tumor protein p53 binding protein 1 Mapped by Literature SNP NAS[9748285]
GLIS2 GLIS family zinc finger 2 Mapped by significant region ISS
MED24 mediator complex subunit 24 Mapped by PBA pathway IDA[10198638]
PHF5A PHD finger protein 5A Mapped by PBA pathway ISS
FOXF1 forkhead box F1 Mapped by significant region IDA[9769171]
WNT11 wingless-type MMTV integration site family, member 11 Mapped by significant region IMP[19847889]
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A Mapped by significant region IDA[18073330]
KAT8 K(lysine) acetyltransferase 8 Mapped by CNV IDA[11742995]; IMP[15960975]
MED30 mediator complex subunit 30 Mapped by PBA pathway IDA[10198638]
MED4 mediator complex subunit 4 Mapped by PBA pathway IDA[10198638]
KLF4 Kruppel-like factor 4 (gut) Mapped by significant region ISS; NAS[9422764]
IRF7 interferon regulatory factor 7 Mapped by LD-proxy IMP[12374802]
MED12 mediator complex subunit 12 Mapped by PBA pathway IDA[10198638]
PSRC1 proline/serine-rich coiled-coil 1 Mapped by CNV ISS[12427559]
NPAT nuclear protein, ataxia-telangiectasia locus Mapped by CNV; Mapped by significant region IDA[18850719]
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) Mapped by significant region IDA[9169153]
AXIN1 axin 1 Mapped by significant region IMP[16601693]
TASP1 taspase, threonine aspartase, 1 Mapped by CNV IMP[14636557]
MED14 mediator complex subunit 14 Mapped by PBA pathway IDA[10198638]
ATMIN ATM interactor Mapped by significant region IDA
NUP62 nucleoporin 62kDa Mapped by PBA pathway IDA[15625236]; ISS
HOXA11 homeobox A11 Mapped by significant region ISS