ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0043065
Name positive regulation of apoptotic process
Type biological process
No. of Genes in ADHDgene  38
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 38)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 4(1/3/0) IEA
CNR1 cannabinoid receptor 1 (brain) 6q14-q15 1(1/0/0) IEA
NET1 neuroepithelial cell transforming 1 10p15 1(1/0/0) IDA
DUSP1 dual specificity phosphatase 1 5q35.1 1(0/1/0) IEA

Genes from other sources Help (count: 34)

Approved Symbol Approved Name Source Evidence[PMID]
KLF11 Kruppel-like factor 11 Mapped by significant region IDA
GAL galanin/GMAP prepropeptide Mapped by CNV; Mapped by significant region IEA
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region IMP[17875758]
WWOX WW domain containing oxidoreductase Mapped by significant region ISS
MEN1 multiple endocrine neoplasia I Mapped by significant region IEA
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Mapped by CNV IDA[18468999]
APC adenomatous polyposis coli Mapped by LD-proxy; Mapped by PBA pathway IMP[17227893]
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region IEA
BAD BCL2-associated agonist of cell death Mapped by significant region IDA[9388232]; IMP[17289999]
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal Mapped by CNV; Mapped by PBA pathway IEA
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region IEA
DAB2IP DAB2 interacting protein Mapped by significant region IDA[12813029]
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 Mapped by significant region IMP[18823379]
HOXA13 homeobox A13 Mapped by significant region IEA
BCLAF1 BCL2-associated transcription factor 1 Mapped by significant region IDA[10330179]
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region IDA
BCL2L11 BCL2-like 11 (apoptosis facilitator) Mapped by LD-proxy IMP[17289999]
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) Mapped by significant region IDA[18818310]
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 Mapped by significant region IEA
FLCN folliculin Mapped by significant region ISS
FOSL1 FOS-like antigen 1 Mapped by significant region IEA
NOX4 NADPH oxidase 4 Mapped by significant region IEA
WNT11 wingless-type MMTV integration site family, member 11 Mapped by significant region IEA
BARD1 BRCA1 associated RING domain 1 Mapped by significant region IMP[15782130]
MAPK9 mitogen-activated protein kinase 9 Mapped by CNV IEA
ZNF622 zinc finger protein 622 Mapped by significant region IDA
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 Mapped by significant region IDA; IMP
HOXA5 homeobox A5 Mapped by significant region IDA[10879542]
PYCARD PYD and CARD domain containing Mapped by CNV IDA[12646168]
ZBTB16 zinc finger and BTB domain containing 16 Mapped by significant region IEA
LPAR1 lysophosphatidic acid receptor 1 Mapped by significant region IEA
FADD Fas (TNFRSF6)-associated via death domain Mapped by significant region IMP
PDIA3 protein disulfide isomerase family A, member 3 Mapped by PBA pathway IEA
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 Mapped by significant region IDA[10411904]