ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006644
Name phospholipid metabolic process
Type biological process
No. of Genes in ADHDgene  61
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 61)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
LPL lipoprotein lipase 8p22 1(0/0/1) ISS[10727238]
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IEA
STS steroid sulfatase (microsomal), isozyme S Xp22.32 3(2/1/0) TAS
ARSB arylsulfatase B 5q14.1 1(0/0/1) TAS
PRKD1 protein kinase D1 14q11 1(0/1/0) TAS

Genes from other sources Help (count: 56)

Approved Symbol Approved Name Source Evidence[PMID]
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) Mapped by PBA pathway TAS
PLA2G5 phospholipase A2, group V Mapped by PBA pathway TAS
PLD1 phospholipase D1, phosphatidylcholine-specific Mapped by PBA pathway TAS
LPCAT1 lysophosphatidylcholine acyltransferase 1 Mapped by LD-proxy; Mapped by significant region TAS
PLCD1 phospholipase C, delta 1 Mapped by PBA pathway TAS[9588182]
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase Mapped by CNV TAS
PLA2G2E phospholipase A2, group IIE Mapped by PBA pathway TAS
PNPLA3 patatin-like phospholipase domain containing 3 Mapped by PBA pathway TAS
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Mapped by CNV TAS
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 Mapped by significant region IDA
LPIN1 lipin 1 Mapped by significant region TAS
ARSJ arylsulfatase family, member J Mapped by CNV TAS
PLCB2 phospholipase C, beta 2 Mapped by PBA pathway TAS[1644792]
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) Mapped by PBA pathway TAS
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 Mapped by PBA pathway TAS
PNPLA8 patatin-like phospholipase domain containing 8 Mapped by PBA pathway TAS
UGCG UDP-glucose ceramide glucosyltransferase Mapped by significant region TAS
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) Mapped by PBA pathway IDA[17069818]; TAS
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 Mapped by significant region TAS
GATA6 GATA binding protein 6 Mapped by significant region IEA
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma Mapped by LD-proxy TAS
MBOAT2 membrane bound O-acyltransferase domain containing 2 Mapped by significant region TAS
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal Mapped by CNV; Mapped by PBA pathway TAS
PLA2G3 phospholipase A2, group III Mapped by PBA pathway TAS
PLA2G2D phospholipase A2, group IID Mapped by PBA pathway TAS
MTMR2 myotubularin related protein 2 Mapped by significant region TAS
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha Mapped by CNV TAS
ACER3 alkaline ceramidase 3 Mapped by significant region TAS
PLA2G1B phospholipase A2, group IB (pancreas) Mapped by PBA pathway TAS
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) Mapped by PBA pathway TAS
PLD6 phospholipase D family, member 6 Mapped by significant region TAS
PLA2G4B phospholipase A2, group IVB (cytosolic) Mapped by PBA pathway TAS
PLD2 phospholipase D2 Mapped by PBA pathway TAS
MBOAT1 membrane bound O-acyltransferase domain containing 1 Mapped by Literature SNP TAS
PLA2G16 phospholipase A2, group XVI Mapped by significant region IDA; TAS
DGAT2 diacylglycerol O-acyltransferase 2 Mapped by significant region TAS
PLA2G10 phospholipase A2, group X Mapped by significant region; Mapped by PBA pathway TAS
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial Mapped by LD-proxy TAS
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region TAS
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 Mapped by significant region TAS
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 Mapped by CNV TAS
SUMF1 sulfatase modifying factor 1 Mapped by CNV TAS
PI4K2B phosphatidylinositol 4-kinase type 2 beta Mapped by CNV TAS
PEMT phosphatidylethanolamine N-methyltransferase Mapped by significant region TAS
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) Mapped by significant region; Mapped by PBA pathway TAS
MGLL monoglyceride lipase Mapped by PBA pathway TAS
CHKA choline kinase alpha Mapped by significant region TAS
SLC44A1 solute carrier family 44 (choline transporter), member 1 Mapped by CNV; Mapped by significant region TAS
PLCE1 phospholipase C, epsilon 1 Mapped by PBA pathway IC[11022048]
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 Mapped by significant region TAS
PLD3 phospholipase D family, member 3 Mapped by PBA pathway TAS
LPCAT4 lysophosphatidylcholine acyltransferase 4 Mapped by CNV TAS
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway TAS
LGALS13 lectin, galactoside-binding, soluble, 13 Mapped by PBA pathway TAS[10527825]
NEU3 sialidase 3 (membrane sialidase) Mapped by significant region TAS
INPPL1 inositol polyphosphate phosphatase-like 1 Mapped by significant region TAS