ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0016491
Name oxidoreductase activity
Type molecular function
No. of Genes in ADHDgene  21
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 21)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FADS1 fatty acid desaturase 1 11q12-q13.1 3(1/2/0) IDA[10601301]
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IDA
GFOD1 glucose-fructose oxidoreductase domain containing 1 6p24.1-p23 1(1/0/0) IEA
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 1(1/0/0) IBA

Genes from other sources Help (count: 17)

Approved Symbol Approved Name Source Evidence[PMID]
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) Mapped by significant region IEA
FOXRED1 FAD-dependent oxidoreductase domain containing 1 Mapped by significant region IEA
WWOX WW domain containing oxidoreductase Mapped by significant region NAS[10861292]; TAS[10786676]
DHRS11 dehydrogenase/reductase (SDR family) member 11 Mapped by CNV IEA
HSDL2 hydroxysteroid dehydrogenase like 2 Mapped by significant region IEA
SUMF1 sulfatase modifying factor 1 Mapped by CNV IEA
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 Mapped by CNV IDA[16401082]
DHRS7B dehydrogenase/reductase (SDR family) member 7B Mapped by significant region IEA
IYD iodotyrosine deiodinase Mapped by CNV IEA
KDM1A lysine (K)-specific demethylase 1A Mapped by LD-proxy IDA[15620353]
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 Mapped by CNV IEA
CYB561A3 cytochrome b561 family, member A3 Mapped by significant region IEA
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 Mapped by significant region IEA
DHRS1 dehydrogenase/reductase (SDR family) member 1 Mapped by significant region IEA
STEAP2 STEAP family member 2, metalloreductase Mapped by PBA pathway IEA
VAT1L vesicle amine transport 1-like Mapped by significant region IEA
HSDL1 hydroxysteroid dehydrogenase like 1 Mapped by CNV; Mapped by significant region IEA