ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006469
Name negative regulation of protein kinase activity
Type biological process
No. of Genes in ADHDgene  17
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 17)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 17q12 1(0/1/0) TAS[10604473]
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 22q11.22 1(0/0/1) IDA[11864573]
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7q35-q36 1(0/0/1) IDA[17255938]

Genes from other sources Help (count: 14)

Approved Symbol Approved Name Source Evidence[PMID]
THY1 Thy-1 cell surface antigen Mapped by significant region ISS
PYDC1 PYD (pyrin domain) containing 1 Mapped by CNV IDA[12656673]
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 Mapped by significant region IDA[15601829]
GSTP1 glutathione S-transferase pi 1 Mapped by significant region IDA[16636664]
CRIPAK cysteine-rich PAK1 inhibitor Mapped by PBA pathway IDA[16278681]
CAV3 caveolin 3 Mapped by Literature SNP ISS
NF2 neurofibromin 2 (merlin) Mapped by PBA pathway IEA
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IEA
SOCS1 suppressor of cytokine signaling 1 Mapped by significant region TAS[9202125]
GADD45G growth arrest and DNA-damage-inducible, gamma Mapped by significant region IEA
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region IDA[9373175]
TSC2 tuberous sclerosis 2 Mapped by significant region ISS
ILK integrin-linked kinase Mapped by CNV IEA
ADORA2A adenosine A2a receptor Mapped by CNV IEA