ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0051898
Name negative regulation of protein kinase B signaling cascade
Type biological process
No. of Genes in ADHDgene  7
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 7)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DRD3 dopamine receptor D3 3q13.3 8(1/7/0) ISS
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 7q21 1(0/0/1) IDA[10760291]
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) ISS
PTPRJ protein tyrosine phosphatase, receptor type, J 11p11.2 1(0/1/0) IMP[19922411]

Genes from other sources Help (count: 3)

Approved Symbol Approved Name Source Evidence[PMID]
FLCN folliculin Mapped by significant region ISS
TSC2 tuberous sclerosis 2 Mapped by significant region ISS
KLF4 Kruppel-like factor 4 (gut) Mapped by significant region IEA