ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0045665
Name negative regulation of neuron differentiation
Type biological process
No. of Genes in ADHDgene  13
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 13)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2p25 1(0/1/0) ISS
CNTN4 contactin 4 3p26.3 1(1/0/0) IMP[14571131]
ISL1 ISL LIM homeobox 1 5q11.2 1(0/1/0) IEA
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 17q11.2 26(13/13/0) IEA

Genes from other sources Help (count: 9)

Approved Symbol Approved Name Source Evidence[PMID]
FOXG1 forkhead box G1 Mapped by significant region IBA
PRPF19 pre-mRNA processing factor 19 Mapped by significant region IEA
IRX3 iroquois homeobox 3 Mapped by CNV IEA
HOXA2 homeobox A2 Mapped by significant region IEA
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway ISS
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region IEA
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 Mapped by significant region IEA
MIB1 mindbomb E3 ubiquitin protein ligase 1 Mapped by significant region IEA
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Mapped by CNV IEA