ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0043524
Name negative regulation of neuron apoptotic process
Type biological process
No. of Genes in ADHDgene  18
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 18)

Literature-origin genes (count: 11)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
CNTFR ciliary neurotrophic factor receptor 9p13 1(1/0/0) IEA
NTF3 neurotrophin 3 12p13 4(1/3/0) IEA
GDNF glial cell derived neurotrophic factor 5p13.1-p12 2(1/1/0) IDA[8493557]
CNTF ciliary neurotrophic factor 11q12 1(1/0/0) IDA[10966616]
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0) ISS
ISL1 ISL LIM homeobox 1 5q11.2 1(0/1/0) ISS
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0) IEA
NR4A2 nuclear receptor subfamily 4, group A, member 2 2q22-q23 2(0/2/0) IEA
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IEA
BDNF brain-derived neurotrophic factor 11p14.1 16(8/8/0) IEA
PARK2 parkin RBR E3 ubiquitin protein ligase 6q25.2-q27 1(1/0/0) IDA

Genes from other sources Help (count: 7)

Approved Symbol Approved Name Source Evidence[PMID]
CHL1 cell adhesion molecule L1-like Mapped by CNV IEA
ADAM8 ADAM metallopeptidase domain 8 Mapped by LD-proxy; Mapped by CNV ISS
CLCF1 cardiotrophin-like cytokine factor 1 Mapped by significant region IDA[11285233]
VEGFB vascular endothelial growth factor B Mapped by significant region IDA[18259607]
ILK integrin-linked kinase Mapped by CNV IEA
ADORA2A adenosine A2a receptor Mapped by CNV IEA
RASA1 RAS p21 protein activator (GTPase activating protein) 1 Mapped by PBA pathway ISS