ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007275
Name multicellular organismal development
Type biological process
No. of Genes in ADHDgene  79
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 79)

Literature-origin genes (count: 10)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 22q11.21 1(1/0/0) TAS[9126485]
HOXB1 homeobox B1 17q21.32 1(0/0/1) NAS[10052460]
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) TAS[8365415]
PRTG protogenin 15q21.3 1(1/0/0) IEA
GFI1B growth factor independent 1B transcription repressor 9q34.13 1(0/1/0) IEA
ADRA1D adrenoceptor alpha 1D 20p13 1(0/1/0) TAS[10820200]
ADRA1B adrenoceptor alpha 1B 5q33.3 2(1/1/0) TAS[10820200]
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2p25 1(0/1/0) TAS[1741406]
TLL2 tolloid-like 2 10q23-q24 1(0/0/1) IEA
CDK20 cyclin-dependent kinase 20 9q22.1 1(0/1/0) IEA

Genes from other sources Help (count: 69)

Approved Symbol Approved Name Source Evidence[PMID]
GGNBP2 gametogenetin binding protein 2 Mapped by CNV IEA
HOXA1 homeobox A1 Mapped by significant region TAS[7622051]
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 Mapped by CNV IEA
TSSK4 testis-specific serine kinase 4 Mapped by significant region IEA
ZNF74 zinc finger protein 74 Mapped by CNV TAS[1639391]
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) Mapped by significant region TAS[7581459]
FES feline sarcoma oncogene Mapped by LD-proxy TAS[6264598]
IGF2 insulin-like growth factor 2 (somatomedin A) Mapped by LD-proxy TAS[6382022]
GRHL1 grainyhead-like 1 (Drosophila) Mapped by significant region IEA
BARX1 BARX homeobox 1 Mapped by significant region NAS
PTP4A1 protein tyrosine phosphatase type IVA, member 1 Mapped by significant region IEA
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 Mapped by significant region IEA
FAT3 FAT atypical cadherin 3 Mapped by significant region IEA
TNP2 transition protein 2 (during histone to protamine replacement) Mapped by significant region IEA
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1 Mapped by significant region IEA
ZFR zinc finger RNA binding protein Mapped by significant region IEA
VENTX VENT homeobox Mapped by CNV IEA
CFDP1 craniofacial development protein 1 Mapped by significant region IEA
HOXA11 homeobox A11 Mapped by significant region ISS
BANP BTG3 associated nuclear protein Mapped by significant region IEA
CATSPER2 cation channel, sperm associated 2 Mapped by LD-proxy IEA
NLRP14 NLR family, pyrin domain containing 14 Mapped by CNV IEA
SPIN1 spindlin 1 Mapped by significant region IEA
GNRHR gonadotropin-releasing hormone receptor Mapped by significant region TAS[10686191]
ANGPTL2 angiopoietin-like 2 Mapped by significant region TAS[10473614]
HEMGN hemogen Mapped by significant region IEA
REG3A regenerating islet-derived 3 alpha Mapped by CNV TAS[8997243]
ZNF521 zinc finger protein 521 Mapped by significant region IEA
MMP11 matrix metallopeptidase 11 (stromelysin 3) Mapped by CNV TAS[7746327]
NPAP1 nuclear pore associated protein 1 Mapped by CNV; Mapped by significant region IEA
PRM2 protamine 2 Mapped by significant region IEA
MTL5 metallothionein-like 5, testis-specific (tesmin) Mapped by CNV; Mapped by significant region IEA
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 Mapped by CNV; Mapped by significant region IEA
UPK2 uroplakin 2 Mapped by significant region TAS[9515818]
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A Mapped by significant region TAS[10551889]
PDGFD platelet derived growth factor D Mapped by significant region IEA
FLII flightless I homolog (Drosophila) Mapped by significant region IEA
CATSPER1 cation channel, sperm associated 1 Mapped by significant region IEA
EBF1 early B-cell factor 1 Mapped by significant region IEA
PRM3 protamine 3 Mapped by significant region IEA
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) Mapped by significant region IEA
HOXA10 homeobox A10 Mapped by significant region TAS[8972230]
OSGIN1 oxidative stress induced growth inhibitor 1 Mapped by CNV; Mapped by significant region IEA
ANO1 anoctamin 1, calcium activated chloride channel Mapped by significant region IEA
ROR2 receptor tyrosine kinase-like orphan receptor 2 Mapped by significant region TAS[1334494]
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 Mapped by significant region TAS[8165126]
TSSK2 testis-specific serine kinase 2 Mapped by CNV IEA
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 Mapped by significant region IEA
RREB1 ras responsive element binding protein 1 Mapped by CNV TAS[8816445]
HOXA9 homeobox A9 Mapped by significant region TAS[8563754]
LMX1B LIM homeobox transcription factor 1, beta Mapped by significant region NAS[9618165]
TXNDC8 thioredoxin domain containing 8 (spermatozoa) Mapped by significant region IEA
STRBP spermatid perinuclear RNA binding protein Mapped by significant region IEA
DOPEY2 dopey family member 2 Mapped by PBA pathway NAS[10950924]
PRM1 protamine 1 Mapped by significant region IEA
SPATA19 spermatogenesis associated 19 Mapped by significant region IEA
FOXL1 forkhead box L1 Mapped by significant region NAS[11078474]
TSHZ2 teashirt zinc finger homeobox 2 Mapped by Literature SNP IEA
PHF3 PHD finger protein 3 Mapped by significant region NAS[11856869]
PIWIL4 piwi-like RNA-mediated gene silencing 4 Mapped by significant region IEA
WDR47 WD repeat domain 47 Mapped by CNV IEA
GADD45G growth arrest and DNA-damage-inducible, gamma Mapped by significant region IEA
PDILT protein disulfide isomerase-like, testis expressed Mapped by significant region IEA
TNP1 transition protein 1 (during histone to protamine replacement) Mapped by significant region IEA
TBC1D32 TBC1 domain family, member 32 Mapped by significant region IEA
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 Mapped by significant region IEA
FOXD4 forkhead box D4 Mapped by CNV NAS
CTNND2 catenin (cadherin-associated protein), delta 2 Mapped by CNV; Mapped by significant region IEA
ACRV1 acrosomal vesicle protein 1 Mapped by significant region TAS[1693291]