ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007507
Name heart development
Type biological process
No. of Genes in ADHDgene  29
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 29)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FGF12 fibroblast growth factor 12 3q28 1(0/1/0) TAS[10049777]
PTPRJ protein tyrosine phosphatase, receptor type, J 11p11.2 1(0/1/0) IEA
ADRBK1 adrenergic, beta, receptor kinase 1 11q13 1(0/1/0) IEA
MAP2K5 mitogen-activated protein kinase kinase 5 15q22.31 1(1/0/0) IEA
TH tyrosine hydroxylase 11p15.5 7(2/5/0) ISS
OXTR oxytocin receptor 3p25 1(0/1/0) IEA

Genes from other sources Help (count: 23)

Approved Symbol Approved Name Source Evidence[PMID]
TXNRD2 thioredoxin reductase 2 Mapped by Literature SNP; Mapped by CNV IEA
TSC2 tuberous sclerosis 2 Mapped by significant region ISS
PKD1 polycystic kidney disease 1 (autosomal dominant) Mapped by significant region IEP[11891195]
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like Mapped by CNV IEA
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 Mapped by LD-proxy TAS[15504738]
PBRM1 polybromo 1 Mapped by LD-proxy IEA
TBX1 T-box 1 Mapped by CNV IMP[14585638]
FOXL1 forkhead box L1 Mapped by significant region IMP
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 Mapped by significant region IEA
GJA1 gap junction protein, alpha 1, 43kDa Mapped by Literature SNP; Mapped by significant region IEA
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region ISS
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) Mapped by significant region IMP
TCF25 transcription factor 25 (basic helix-loop-helix) Mapped by significant region NAS[16574069]
ADAM19 ADAM metallopeptidase domain 19 Mapped by significant region IEA
MED12 mediator complex subunit 12 Mapped by PBA pathway IEA
PLCE1 phospholipase C, epsilon 1 Mapped by PBA pathway TAS[11022047]
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region IEA
OXCT1 3-oxoacid CoA transferase 1 Mapped by significant region IEA
FOXF1 forkhead box F1 Mapped by significant region IMP[19500772]
IRX4 iroquois homeobox 4 Mapped by significant region IEA
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway ISS
EDNRA endothelin receptor type A Mapped by PBA pathway IEA
FGF19 fibroblast growth factor 19 Mapped by significant region IEA