ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005234
Name extracellular-glutamate-gated ion channel activity
Type molecular function
No. of Genes in ADHDgene  8
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 8)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 4(1/3/0) IEA
GRIK1 glutamate receptor, ionotropic, kainate 1 21q22 1(0/0/1) IEA
GRID2 glutamate receptor, ionotropic, delta 2 4q22 1(0/0/1) IEA
GRIK4 glutamate receptor, ionotropic, kainate 4 11q23.3 1(0/1/0) IEA
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12p12 2(1/1/0) IEA

Genes from other sources Help (count: 3)

Approved Symbol Approved Name Source Evidence[PMID]
STX1B syntaxin 1B Mapped by CNV TAS[8105537]
GRIA4 glutamate receptor, ionotropic, AMPA 4 Mapped by significant region IEA
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region IEA