ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0030198
Name	extracellular matrix organization
Type	Biological Process
No. of Genes in ADHDgene	31
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 31)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
FURIN	furin (paired basic amino acid cleaving enzyme)	15q26.1	1(0/0/1)
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	11q21-q22	1(0/0/1)

Genes from other sources (count: 29)

Approved Symbol	Approved Name	Source
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	Mapped by significant region
APLP2	amyloid beta (A4) precursor-like protein 2	Mapped by significant region
MMP11	matrix metallopeptidase 11 (stromelysin 3)	Mapped by CNV
GLT25D2	glycosyltransferase 25 domain containing 2	Mapped by significant region
MMP10	matrix metallopeptidase 10 (stromelysin 2)	Mapped by significant region
CMA1	chymase 1, mast cell	Mapped by significant region
FOXF1	forkhead box F1	Mapped by significant region
CRISPLD2	cysteine-rich secretory protein LCCL domain containing 2	Mapped by CNV; Mapped by significant region
COL8A1	collagen, type VIII, alpha 1	Mapped by CNV
MMP13	matrix metallopeptidase 13 (collagenase 3)	Mapped by significant region
MPZL3	myelin protein zero-like 3	Mapped by significant region
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	Mapped by CNV
CTSG	cathepsin G	Mapped by significant region
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	Mapped by significant region
TLL1	tolloid-like 1	Mapped by LD-proxy; Mapped by literature SNP
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	Mapped by significant region
CTRB1	chymotrypsinogen B1	Mapped by significant region
MMP16	matrix metallopeptidase 16 (membrane-inserted)	Mapped by CNV
COL15A1	collagen, type XV, alpha 1	Mapped by significant region
TNR	tenascin R (restrictin, janusin)	Mapped by significant region
COL27A1	collagen, type XXVII, alpha 1	Mapped by significant region
OLFML2B	olfactomedin-like 2B	Mapped by CNV
EGFLAM	EGF-like, fibronectin type III and laminin G domains	Mapped by significant region
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	Mapped by significant region
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	Mapped by CNV; Mapped by literature SNP
SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	Mapped by significant region
CTRB2	chymotrypsinogen B2	Mapped by significant region
OLFML2A	olfactomedin-like 2A	Mapped by significant region
COL10A1	collagen, type X, alpha 1	Mapped by significant region