ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0007173
Name	epidermal growth factor receptor signaling pathway
Type	biological process
No. of Genes in ADHDgene	32
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 32)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
GSK3B	glycogen synthase kinase 3 beta	3q13.3	1(1/0/0)	TAS
ADRBK1	adrenergic, beta, receptor kinase 1	11q13	1(0/1/0)	TAS
EREG	epiregulin	4q21.21	1(0/0/1)	ISS

Genes from other sources (count: 29)

Approved Symbol	Approved Name	Source	Evidence[PMID]
MLST8	MTOR associated protein, LST8 homolog (S. cerevisiae)	Mapped by significant region	TAS
BAD	BCL2-associated agonist of cell death	Mapped by significant region	TAS
MAPKAP1	mitogen-activated protein kinase associated protein 1	Mapped by significant region	TAS
PDPK1	3-phosphoinositide dependent protein kinase-1	Mapped by significant region	TAS
CBL	Cbl proto-oncogene, E3 ubiquitin protein ligase	Mapped by significant region	TAS
ADCY4	adenylate cyclase 4	Mapped by significant region	TAS
ADCY9	adenylate cyclase 9	Mapped by significant region	TAS
REPS2	RALBP1 associated Eps domain containing 2	Mapped by CNV	TAS[9422736]
GAREM	GRB2 associated, regulator of MAPK1	Mapped by significant region	IDA[19509291]
RICTOR	RPTOR independent companion of MTOR, complex 2	Mapped by significant region	TAS
VIL1	villin 1	Mapped by significant region	IDA[17229814]
ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	Mapped by CNV	TAS
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region	ISS
RPS6KB2	ribosomal protein S6 kinase, 70kDa, polypeptide 2	Mapped by significant region	TAS
NCK2	NCK adaptor protein 2	Mapped by PBA pathway	TAS[9737977]
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	Mapped by Literature SNP	TAS
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy	TAS
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	Mapped by CNV	TAS
ADCY2	adenylate cyclase 2 (brain)	Mapped by significant region	TAS
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	Mapped by significant region	TAS[8808684]
ERBB2	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2	Mapped by LD-proxy	NAS[15504738]
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region	IDA[12743035]; TAS
UBC	ubiquitin C	Mapped by CNV	TAS
UBB	ubiquitin B	Mapped by significant region	TAS
PLCE1	phospholipase C, epsilon 1	Mapped by PBA pathway	NAS[11022048]
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Mapped by significant region	TAS
TSC2	tuberous sclerosis 2	Mapped by significant region	TAS
ADCY3	adenylate cyclase 3	Mapped by LD-proxy	TAS
MAPK3	mitogen-activated protein kinase 3	Mapped by CNV	TAS