ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005789
Name endoplasmic reticulum membrane
Type cellular component
No. of Genes in ADHDgene  159
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 159)

Literature-origin genes (count: 11)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
STS steroid sulfatase (microsomal), isozyme S Xp22.32 3(2/1/0) TAS
ANO5 anoctamin 5 11p15.1 1(0/0/1) IEA
NR3C2 nuclear receptor subfamily 3, group C, member 2 4q31 1(0/1/0) IEA
DRD1 dopamine receptor D1 5q34-q35 8(5/3/0) IEA
FADS2 fatty acid desaturase 2 11q12.2 3(3/0/0) TAS
DHCR7 7-dehydrocholesterol reductase 11q13.4 1(0/0/1) TAS
LMAN2L lectin, mannose-binding 2-like 2q11.1 1(1/0/0) IDA[12609988]
SEC16B SEC16 homolog B (S. cerevisiae) 1q25.2 1(0/1/0) IEA
FADS1 fatty acid desaturase 1 11q12-q13.1 3(1/2/0) TAS
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 2q37 1(0/0/1) TAS
ELOVL6 ELOVL fatty acid elongase 6 4q25 1(0/0/1) TAS

Genes from other sources Help (count: 148)

Approved Symbol Approved Name Source Evidence[PMID]
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 Mapped by LD-proxy TAS
DUOXA2 dual oxidase maturation factor 2 Mapped by CNV IEA
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 Mapped by Literature SNP IEA
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) Mapped by significant region IDA[19723497]
UGT1A5 UDP glucuronosyltransferase 1 family, polypeptide A5 Mapped by LD-proxy IEA
ALG10 ALG10, alpha-1,2-glucosyltransferase Mapped by CNV IEA
ACER3 alkaline ceramidase 3 Mapped by significant region TAS
ALG8 ALG8, alpha-1,3-glucosyltransferase Mapped by significant region TAS
TAPBP TAP binding protein (tapasin) Mapped by LD-proxy IDA[11884415]
ERGIC3 ERGIC and golgi 3 Mapped by PBA pathway IEA
LPCAT4 lysophosphatidylcholine acyltransferase 4 Mapped by CNV TAS
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 Mapped by significant region IEA
RAB2A RAB2A, member RAS oncogene family Mapped by PBA pathway IEA
RCE1 Ras converting CAAX endopeptidase 1 Mapped by significant region IDA[19188362]
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Mapped by CNV TAS
PIGL phosphatidylinositol glycan anchor biosynthesis, class L Mapped by significant region TAS
TRIQK triple QxxK/R motif containing Mapped by LD-proxy IEA
TLR9 toll-like receptor 9 Mapped by LD-proxy TAS
FKBP2 FK506 binding protein 2, 13kDa Mapped by significant region IEA
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q Mapped by significant region TAS
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 Mapped by Literature SNP IEA
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 Mapped by significant region IEA
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) Mapped by significant region TAS
ATL3 atlastin GTPase 3 Mapped by significant region IEA
TMEM132A transmembrane protein 132A Mapped by significant region IEA
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 Mapped by significant region IEA
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) Mapped by LD-proxy TAS
UGT2B11 UDP glucuronosyltransferase 2 family, polypeptide B11 Mapped by significant region IEA
SREBF1 sterol regulatory element binding transcription factor 1 Mapped by significant region TAS
SYVN1 synovial apoptosis inhibitor 1, synoviolin Mapped by significant region TAS
STIM2 stromal interaction molecule 2 Mapped by CNV IEA
FITM1 fat storage-inducing transmembrane protein 1 Mapped by significant region ISS[18160536]
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) Mapped by significant region TAS
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Mapped by significant region TAS
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Mapped by Literature SNP IDA[11402072]; TAS
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 Mapped by PBA pathway IEA
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) Mapped by significant region TAS
AADAC arylacetamide deacetylase Mapped by PBA pathway IDA[19339378]
CNIH2 cornichon family AMPA receptor auxiliary protein 2 Mapped by significant region IEA
CANX calnexin Mapped by CNV IDA[19723497]
SIGMAR1 sigma non-opioid intracellular receptor 1 Mapped by LD-proxy IEA
MOGAT2 monoacylglycerol O-acyltransferase 2 Mapped by significant region IEA
SEC22C SEC22 vesicle trafficking protein homolog C (S. cerevisiae) Mapped by PBA pathway IEA
SGK1 serum/glucocorticoid regulated kinase 1 Mapped by significant region IEA
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 Mapped by significant region IEA
DUOXA1 dual oxidase maturation factor 1 Mapped by CNV IEA
SERINC1 serine incorporator 1 Mapped by significant region ISS
SC5D sterol-C5-desaturase Mapped by significant region TAS
PIGW phosphatidylinositol glycan anchor biosynthesis, class W Mapped by CNV TAS
TXNDC11 thioredoxin domain containing 11 Mapped by significant region IEA
PAPPA-AS1 PAPPA antisense RNA 1 Mapped by significant region IEA
EI24 etoposide induced 2.4 Mapped by significant region IEA
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 Mapped by CNV TAS
LPIN1 lipin 1 Mapped by significant region TAS
NOMO2 NODAL modulator 2 Mapped by significant region IDA[17261586]
FA2H fatty acid 2-hydroxylase Mapped by significant region IEA
PIGB phosphatidylinositol glycan anchor biosynthesis, class B Mapped by LD-proxy IDA[8861954]; TAS
RTN3 reticulon 3 Mapped by significant region IEA
SORT1 sortilin 1 Mapped by CNV IEA
PNPLA8 patatin-like phospholipase domain containing 8 Mapped by PBA pathway TAS
LPCAT1 lysophosphatidylcholine acyltransferase 1 Mapped by LD-proxy; Mapped by significant region TAS
ALG9 ALG9, alpha-1,2-mannosyltransferase Mapped by significant region TAS
LTC4S leukotriene C4 synthase Mapped by CNV IEA
ERP44 endoplasmic reticulum protein 44 Mapped by significant region IDA[11847130]
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 Mapped by significant region IEA
SQLE squalene epoxidase Mapped by CNV TAS
RHBDF1 rhomboid 5 homolog 1 (Drosophila) Mapped by significant region IDA[18832597]
PIEZO1 piezo-type mechanosensitive ion channel component 1 Mapped by significant region IEA
DGAT2 diacylglycerol O-acyltransferase 2 Mapped by significant region TAS
SEC11C SEC11 homolog C (S. cerevisiae) Mapped by significant region TAS
SEZ6L2 seizure related 6 homolog (mouse)-like 2 Mapped by CNV IEA
GJA1 gap junction protein, alpha 1, 43kDa Mapped by Literature SNP; Mapped by significant region TAS
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Mapped by CNV TAS
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 Mapped by significant region TAS
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 Mapped by significant region IEA
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase Mapped by CNV TAS
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) Mapped by PBA pathway IEA
MBOAT1 membrane bound O-acyltransferase domain containing 1 Mapped by Literature SNP TAS
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) Mapped by PBA pathway TAS
SRPR signal recognition particle receptor (docking protein) Mapped by significant region TAS
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 Mapped by LD-proxy TAS
OCA2 oculocutaneous albinism II Mapped by CNV; Mapped by significant region IDA[19116314]
LMAN1 lectin, mannose-binding, 1 Mapped by LD-proxy; Mapped by significant region; Mapped by PBA pathway IEA
STX18 syntaxin 18 Mapped by PBA pathway IEA
PNPLA3 patatin-like phospholipase domain containing 3 Mapped by PBA pathway TAS
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 Mapped by LD-proxy TAS
NOX4 NADPH oxidase 4 Mapped by significant region IEA
BFAR bifunctional apoptosis regulator Mapped by significant region IEA
TRIM13 tripartite motif containing 13 Mapped by LD-proxy IDA[17314412]
PLD1 phospholipase D1, phosphatidylcholine-specific Mapped by PBA pathway TAS
MOXD1 monooxygenase, DBH-like 1 Mapped by significant region IEA
SRD5A3 steroid 5 alpha-reductase 3 Mapped by LD-proxy TAS
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 Mapped by LD-proxy TAS
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 Mapped by Literature SNP TAS
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 Mapped by significant region IEA
ERGIC2 ERGIC and golgi 2 Mapped by PBA pathway IEA
XYLT1 xylosyltransferase I Mapped by CNV; Mapped by significant region IEA
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) Mapped by significant region TAS
MGLL monoglyceride lipase Mapped by PBA pathway TAS
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase Mapped by significant region TAS
PDIA6 protein disulfide isomerase family A, member 6 Mapped by significant region TAS
ZW10 zw10 kinetochore protein Mapped by significant region; Mapped by PBA pathway IEA
PLD2 phospholipase D2 Mapped by PBA pathway TAS
KLHL14 kelch-like family member 14 Mapped by significant region IEA
ERN2 endoplasmic reticulum to nucleus signaling 2 Mapped by significant region IEA
PYURF PIGY upstream reading frame Mapped by CNV IDA[16162815]
BET1 Bet1 golgi vesicular membrane trafficking protein Mapped by PBA pathway IEA
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 Mapped by significant region TAS[8099587]
ATP10A ATPase, class V, type 10A Mapped by CNV; Mapped by significant region IEA
PEMT phosphatidylethanolamine N-methyltransferase Mapped by significant region TAS
ATF6 activating transcription factor 6 Mapped by CNV TAS
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 Mapped by LD-proxy IEA
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) Mapped by PBA pathway IEA
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) Mapped by PBA pathway IEA
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 Mapped by Literature SNP TAS
PANX1 pannexin 1 Mapped by significant region IEA
LMF1 lipase maturation factor 1 Mapped by significant region IEA
PDCD6 programmed cell death 6 Mapped by significant region IEA
SEC23A Sec23 homolog A (S. cerevisiae) Mapped by LD-proxy TAS
FADS3 fatty acid desaturase 3 Mapped by LD-proxy; Mapped by significant region IEA
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 Mapped by significant region IEA
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) Mapped by significant region TAS
CLSTN2 calsyntenin 2 Mapped by CNV IEA
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 Mapped by CNV TAS
TMED2 transmembrane emp24 domain trafficking protein 2 Mapped by CNV IEA
ELOVL7 ELOVL fatty acid elongase 7 Mapped by CNV TAS
SCFD1 sec1 family domain containing 1 Mapped by significant region IEA
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 Mapped by significant region IEA
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 Mapped by significant region TAS
UNC93B1 unc-93 homolog B1 (C. elegans) Mapped by significant region TAS
ARHGAP32 Rho GTPase activating protein 32 Mapped by significant region IEA
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) Mapped by PBA pathway IEA
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 Mapped by significant region TAS
MBOAT2 membrane bound O-acyltransferase domain containing 2 Mapped by significant region TAS
STX17 syntaxin 17 Mapped by significant region IEA
MBTPS1 membrane-bound transcription factor peptidase, site 1 Mapped by CNV; Mapped by significant region IEA
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 Mapped by LD-proxy NAS
TM7SF2 transmembrane 7 superfamily member 2 Mapped by significant region TAS
HMOX2 heme oxygenase (decycling) 2 Mapped by significant region TAS
PLD3 phospholipase D family, member 3 Mapped by PBA pathway IEA
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y Mapped by CNV IDA[16162815]
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase Mapped by significant region TAS
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 Mapped by significant region TAS
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) Mapped by PBA pathway TAS
VKORC1 vitamin K epoxide reductase complex, subunit 1 Mapped by CNV TAS
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 Mapped by significant region IEA
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) Mapped by significant region; Mapped by PBA pathway TAS
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) Mapped by significant region ISS; TAS