ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0003682
Name	chromatin binding
Type	molecular function
No. of Genes in ADHDgene	50
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 50)

Literature-origin genes (count: 6)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	9q21.32	1(1/0/0)	IEA
FOXP2	forkhead box P2	7q31	1(1/0/0)	IBA
H2AFY	H2A histone family, member Y	5q31.1	1(0/1/0)	IEA
FOXP1	forkhead box P1	3p14.1	1(0/0/1)	IBA
ISL1	ISL LIM homeobox 1	5q11.2	1(0/1/0)	IEA
TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	9q21.32	1(1/0/0)	IEA

Genes from other sources (count: 44)

Approved Symbol	Approved Name	Source	Evidence[PMID]
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	Mapped by significant region	IEA
MTA2	metastasis associated 1 family, member 2	Mapped by significant region	IEA
ASF1A	anti-silencing function 1A histone chaperone	Mapped by significant region	NAS[10759893]
EED	embryonic ectoderm development	Mapped by significant region	IEA
UXT	ubiquitously-expressed, prefoldin-like chaperone	Mapped by PBA pathway	IDA
TADA2A	transcriptional adaptor 2A	Mapped by CNV	IEA
RNF2	ring finger protein 2	Mapped by significant region	IEA
MYB	v-myb avian myeloblastosis viral oncogene homolog	Mapped by significant region	IEA
BARX2	BARX homeobox 2	Mapped by significant region	IEA
RELA	v-rel avian reticuloendotheliosis viral oncogene homolog A	Mapped by significant region	IDA[19058135]
RCOR2	REST corepressor 2	Mapped by significant region	IEA
SSRP1	structure specific recognition protein 1	Mapped by significant region	IEA
NIPBL	Nipped-B homolog (Drosophila)	Mapped by significant region	IEA
HINFP	histone H4 transcription factor	Mapped by significant region	IEA
CREBBP	CREB binding protein	Mapped by significant region	IEA
MED12	mediator complex subunit 12	Mapped by PBA pathway	IEA
WDR82	WD repeat domain 82	Mapped by LD-proxy	IEA
NUP62	nucleoporin 62kDa	Mapped by PBA pathway	NAS[11852044]
SREBF1	sterol regulatory element binding transcription factor 1	Mapped by significant region	IEA
NCOR2	nuclear receptor corepressor 2	Mapped by CNV	IEA
CDCA5	cell division cycle associated 5	Mapped by significant region	TAS[15837422]
YAP1	Yes-associated protein 1	Mapped by significant region	IEA
NR5A1	nuclear receptor subfamily 5, group A, member 1	Mapped by significant region	IEA
CENPB	centromere protein B, 80kDa	Mapped by CNV	NAS[1893793]
CRAMP1L	Crm, cramped-like (Drosophila)	Mapped by significant region	IEA
SMC3	structural maintenance of chromosomes 3	Mapped by PBA pathway	IEA
NSD1	nuclear receptor binding SET domain protein 1	Mapped by PBA pathway	ISS
SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	Mapped by significant region	IEA
GATA6	GATA binding protein 6	Mapped by significant region	IEA
MEN1	multiple endocrine neoplasia I	Mapped by significant region	IEA
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	Mapped by CNV	IDA[19343227]
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	Mapped by CNV	IDA[18063578]
RCC1	regulator of chromosome condensation 1	Mapped by PBA pathway	IDA[2677018]
PBRM1	polybromo 1	Mapped by LD-proxy	NAS[11078522]
RNF20	ring finger protein 20, E3 ubiquitin protein ligase	Mapped by significant region	IEA
NCOA6	nuclear receptor coactivator 6	Mapped by PBA pathway	ISS
MTA3	metastasis associated 1 family, member 3	Mapped by Literature SNP	IEA
SMC1A	structural maintenance of chromosomes 1A	Mapped by PBA pathway	IDA[11076961]
HIRA	histone cell cycle regulator	Mapped by CNV	IEA
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway	IMP[17641689]
ARID3C	AT rich interactive domain 3C (BRIGHT-like)	Mapped by LD-proxy	IEA
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	Mapped by significant region	ISS
RAN	RAN, member RAS oncogene family	Mapped by PBA pathway	TAS[1961752]
KDM1A	lysine (K)-specific demethylase 1A	Mapped by LD-proxy	IDA