ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0034641
Name cellular nitrogen compound metabolic process
Type biological process
No. of Genes in ADHDgene  30
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 30)

Literature-origin genes (count: 10)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11p11.2 1(0/0/1) TAS
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 7p12.1 6(5/1/0) TAS
PNMT phenylethanolamine N-methyltransferase 17q 3(2/1/0) TAS
AANAT aralkylamine N-acetyltransferase 17q25.1 1(0/0/1) TAS
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 21(12/9/0) TAS
TPH1 tryptophan hydroxylase 1 11p15.3-p14 6(2/4/0) TAS
TDO2 tryptophan 2,3-dioxygenase 4q31-q32 1(1/0/0) TAS
TH tyrosine hydroxylase 11p15.5 7(2/5/0) TAS
ASMT acetylserotonin O-methyltransferase Xp22.3 and Yp11.3 1(1/0/0) TAS
TPH2 tryptophan hydroxylase 2 12q15 11(8/3/0) TAS

Genes from other sources Help (count: 20)

Approved Symbol Approved Name Source Evidence[PMID]
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 Mapped by significant region TAS
ACAD8 acyl-CoA dehydrogenase family, member 8 Mapped by CNV; Mapped by significant region TAS
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) Mapped by significant region TAS
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 Mapped by significant region TAS
SHMT1 serine hydroxymethyltransferase 1 (soluble) Mapped by significant region TAS
PAOX polyamine oxidase (exo-N4-amino) Mapped by CNV TAS
GLUL glutamate-ammonia ligase Mapped by significant region TAS
ACAT1 acetyl-CoA acetyltransferase 1 Mapped by CNV; Mapped by significant region TAS
AUH AU RNA binding protein/enoyl-CoA hydratase Mapped by significant region TAS
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) Mapped by significant region TAS
HIBADH 3-hydroxyisobutyrate dehydrogenase Mapped by significant region TAS
AGXT2 alanine--glyoxylate aminotransferase 2 Mapped by significant region TAS
PRODH proline dehydrogenase (oxidase) 1 Mapped by CNV TAS
ARG1 arginase 1 Mapped by significant region TAS
HAAO 3-hydroxyanthranilate 3,4-dioxygenase Mapped by LD-proxy TAS
IYD iodotyrosine deiodinase Mapped by CNV TAS
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 Mapped by significant region TAS
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 Mapped by significant region TAS
ODC1 ornithine decarboxylase 1 Mapped by significant region TAS
CKMT1A creatine kinase, mitochondrial 1A Mapped by LD-proxy TAS