ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0009986
Name cell surface
Type cellular component
No. of Genes in ADHDgene  75
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 75)

Literature-origin genes (count: 12)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10q21 2(0/2/0) ISS
PTPRJ protein tyrosine phosphatase, receptor type, J 11p11.2 1(0/1/0) IDA[12913111]
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3p25.3 1(0/1/0) IEA
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 5p13 2(1/1/0) IEA
NRXN1 neurexin 1 2p16.3 1(0/1/0) IDA; ISS
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0) IDA[16597614]; NAS[11923311]
LPL lipoprotein lipase 8p22 1(0/0/1) IEA
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) IDA[17470632]
FURIN furin (paired basic amino acid cleaving enzyme) 15q26.1 1(0/0/1) IDA[16537537]
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0) IEA
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12p12 2(1/1/0) ISS
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 4(1/3/0) ISS

Genes from other sources Help (count: 63)

Approved Symbol Approved Name Source Evidence[PMID]
CD6 CD6 molecule Mapped by significant region IDA[12493773]
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 Mapped by significant region ISS
STX4 syntaxin 4 Mapped by CNV IDA[15576373]
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Mapped by significant region IDA[12493773]
HSPA8 heat shock 70kDa protein 8 Mapped by significant region IDA[12493773]
NCAM1 neural cell adhesion molecule 1 Mapped by significant region IDA[10766765]
ADAM17 ADAM metallopeptidase domain 17 Mapped by significant region IDA[18625725]
CTSG cathepsin G Mapped by significant region IEA
PRLR prolactin receptor Mapped by significant region IDA[10585417]
TRPV2 transient receptor potential cation channel, subfamily V, member 2 Mapped by significant region IEA
TIGIT T cell immunoreceptor with Ig and ITIM domains Mapped by LD-proxy IDA[19011627]
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mapped by CNV IDA[12782713]
WNT6 wingless-type MMTV integration site family, member 6 Mapped by significant region IEA
GREM1 gremlin 1, DAN family BMP antagonist Mapped by CNV; Mapped by significant region IEA
FZD4 frizzled class receptor 4 Mapped by significant region IDA[19643732]
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 Mapped by significant region ISS
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) Mapped by LD-proxy IDA
KLHL20 kelch-like family member 20 Mapped by significant region IDA[12493773]
LAYN layilin Mapped by significant region ISS
PDIA3 protein disulfide isomerase family A, member 3 Mapped by PBA pathway IDA[19995400]
SPN sialophorin Mapped by CNV IDA
TRPC4 transient receptor potential cation channel, subfamily C, member 4 Mapped by PBA pathway IDA[19996314]
MMP16 matrix metallopeptidase 16 (membrane-inserted) Mapped by CNV IEA
PCSK6 proprotein convertase subtilisin/kexin type 6 Mapped by CNV IDA[12535616]
GHR growth hormone receptor Mapped by CNV; Mapped by significant region IDA[8137822]
CRYAB crystallin, alpha B Mapped by significant region IEA
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 Mapped by significant region IDA[12493773]
TNR tenascin R Mapped by significant region IEA
CXCR2 chemokine (C-X-C motif) receptor 2 Mapped by significant region IDA[10878382]
AAMP angio-associated, migratory cell protein Mapped by significant region IDA[10329261]
RC3H2 ring finger and CCCH-type domains 2 Mapped by significant region IDA[10938276]
NLGN1 neuroligin 1 Mapped by CNV IBA; ISS
DCBLD2 discoidin, CUB and LCCL domain containing 2 Mapped by CNV IDA[11447234]
RTN4R reticulon 4 receptor Mapped by CNV IDA
GPRC6A G protein-coupled receptor, class C, group 6, member A Mapped by CNV; Mapped by significant region IEA
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A Mapped by significant region IEA
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 Mapped by LD-proxy IEA
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IBA
AQP11 aquaporin 11 Mapped by significant region IDA[16650285]
BACE1 beta-site APP-cleaving enzyme 1 Mapped by significant region IEA
APOA4 apolipoprotein A-IV Mapped by significant region IDA[1935934]
LPAR1 lysophosphatidic acid receptor 1 Mapped by significant region IDA[19306925]
DSCAML1 Down syndrome cell adhesion molecule like 1 Mapped by significant region IDA[11453658]
CNTNAP2 contactin associated protein-like 2 Mapped by CNV IDA[19706678]
STRC stereocilin Mapped by LD-proxy IEA
TNN tenascin N Mapped by significant region IEA
PLA2G5 phospholipase A2, group V Mapped by PBA pathway IEA
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 Mapped by significant region IDA[18397322]
SORT1 sortilin 1 Mapped by CNV IDA[10085125]
PTPRK protein tyrosine phosphatase, receptor type, K Mapped by CNV; Mapped by significant region IDA[18276111]
CAV3 caveolin 3 Mapped by Literature SNP IEA
SCARB1 scavenger receptor class B, member 1 Mapped by CNV IEA
MSLN mesothelin Mapped by significant region IEA
ADAM8 ADAM metallopeptidase domain 8 Mapped by LD-proxy; Mapped by CNV IDA[17548643]
RTN4RL2 reticulon 4 receptor-like 2 Mapped by significant region IDA
AMBP alpha-1-microglobulin/bikunin precursor Mapped by significant region IEA
MMP25 matrix metallopeptidase 25 Mapped by significant region IDA[12493773]
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) Mapped by PBA pathway IDA[10521508]
ERP44 endoplasmic reticulum protein 44 Mapped by significant region IDA[19995400]
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 Mapped by significant region IDA[10513816]
SLC46A2 solute carrier family 46, member 2 Mapped by significant region IEA
FAM89B family with sequence similarity 89, member B Mapped by significant region IEA
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) Mapped by significant region IEA