ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0008219
Name cell death
Type biological process
No. of Genes in ADHDgene  33
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 33)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DPP6 dipeptidyl-peptidase 6 7q36.2 1(1/0/0) IEA
GRM1 glutamate receptor, metabotropic 1 6q24 1(1/0/0) IEA
PARK2 parkin RBR E3 ubiquitin protein ligase 6q25.2-q27 1(1/0/0) IDA
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 70(43/26/1) IEA
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 13(7/6/0) IEA
ATXN1 ataxin 1 6p23 1(0/0/1) IEA
ATXN2 ataxin 2 12q23-q24.1 1(0/0/1) IEA

Genes from other sources Help (count: 26)

Approved Symbol Approved Name Source Evidence[PMID]
IGHMBP2 immunoglobulin mu binding protein 2 Mapped by CNV; Mapped by significant region IEA
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) Mapped by PBA pathway IEA
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 Mapped by CNV IDA[10891486]; ISS
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit Mapped by PBA pathway IDA[16595610]
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) Mapped by significant region IEA
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 Mapped by significant region IDA[14712213]
SPTBN2 spectrin, beta, non-erythrocytic 2 Mapped by significant region IEA
SIGMAR1 sigma non-opioid intracellular receptor 1 Mapped by LD-proxy IEA
AXIN1 axin 1 Mapped by significant region IBA
FBXO7 F-box protein 7 Mapped by LD-proxy IEA
KIAA0196 KIAA0196 Mapped by CNV IEA
PNPLA8 patatin-like phospholipase domain containing 8 Mapped by PBA pathway IDA[15695510]
DAGLA diacylglycerol lipase, alpha Mapped by significant region IEA
FA2H fatty acid 2-hydroxylase Mapped by significant region IEA
GAN gigaxonin Mapped by significant region IEA
PANK2 pantothenate kinase 2 Mapped by CNV IEA
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 Mapped by significant region IEA
OPTN optineurin Mapped by PBA pathway IEA
NUP62 nucleoporin 62kDa Mapped by PBA pathway IMP[11244088]; ISS
REEP1 receptor accessory protein 1 Mapped by CNV IEA
FOLR1 folate receptor 1 (adult) Mapped by significant region IEA
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) Mapped by significant region IEA
MAP3K11 mitogen-activated protein kinase kinase kinase 11 Mapped by significant region IEA
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal Mapped by CNV; Mapped by PBA pathway IEA
TPP1 tripeptidyl peptidase I Mapped by CNV IEA
FUS fused in sarcoma Mapped by CNV IEA