ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0000075
Name cell cycle checkpoint
Type biological process
No. of Genes in ADHDgene  21
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 21)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 7p22 1(0/1/0) TAS
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11p11.2 1(0/0/1) TAS

Genes from other sources Help (count: 19)

Approved Symbol Approved Name Source Evidence[PMID]
SMC1A structural maintenance of chromosomes 1A Mapped by PBA pathway IDA[11877377]
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 Mapped by significant region TAS
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region TAS
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) Mapped by significant region TAS
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 Mapped by significant region TAS
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 Mapped by significant region TAS
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) Mapped by significant region TAS
CHEK1 checkpoint kinase 1 Mapped by significant region TAS
RAD1 RAD1 homolog (S. pombe) Mapped by significant region NAS[9660799]; TAS
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 Mapped by significant region TAS
CDC26 cell division cycle 26 Mapped by significant region TAS
RBBP8 retinoblastoma binding protein 8 Mapped by significant region TAS[10764811]
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region TAS
UBB ubiquitin B Mapped by significant region TAS
CDC45 cell division cycle 45 Mapped by CNV TAS
ANAPC4 anaphase promoting complex subunit 4 Mapped by CNV TAS
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region IEA
DDB1 damage-specific DNA binding protein 1, 127kDa Mapped by significant region IMP[17088560]
UBC ubiquitin C Mapped by CNV TAS