ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0007155
Name	cell adhesion
Type	Biological Process
No. of Genes in ADHDgene	86
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 86)

Literature-origin genes (count: 10)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
NRXN1	neurexin 1	2p16.3	1(0/1/0)
ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)	17p13	1(0/0/1)
CNTN5	contactin 5	11q21-q22.2	1(0/0/1)
ITGA11	integrin, alpha 11	15q22.3-q23	1(0/0/1)	TAS[10486209]
MYBPC1	myosin binding protein C, slow type	12q32	1(0/1/0)
NEGR1	neuronal growth regulator 1	1p31.1	1(1/0/0)
MOG	myelin oligodendrocyte glycoprotein	6p22-p21.3	1(0/1/0)
HES1	hairy and enhancer of split 1, (Drosophila)	3q28-q29	1(1/0/0)
SDK2	sidekick homolog 2 (chicken)	17q21.31	1(0/1/0)
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	22q11.21	1(1/0/0)

Genes from other sources (count: 76)

Approved Symbol	Approved Name	Source	Evidence[PMID]
GPNMB	glycoprotein (transmembrane) nmb	Mapped by CNV; Mapped by significant region
DCBLD2	discoidin, CUB and LCCL domain containing 2	Mapped by CNV
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	Mapped by LD-proxy	TAS[10942362]
SPAM1	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)	Mapped by CNV
CHST10	carbohydrate sulfotransferase 10	Mapped by CNV	TAS[9478973]
PTPRK	protein tyrosine phosphatase, receptor type, K	Mapped by CNV; Mapped by significant region	IMP[15899872]
DCBLD1	discoidin, CUB and LCCL domain containing 1	Mapped by significant region
LAMC1	laminin, gamma 1 (formerly LAMB2)	Mapped by significant region	IDA[15159456]
CNTN6	contactin 6	Mapped by CNV
DSC3	desmocollin 3	Mapped by significant region	TAS[7929347]
FLRT3	fibronectin leucine rich transmembrane protein 3	Mapped by CNV
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	Mapped by significant region	TAS[2384753]
NINJ1	ninjurin 1	Mapped by significant region
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	Mapped by CNV	NAS[8103515]
CNTNAP2	contactin associated protein-like 2	Mapped by CNV
TNC	tenascin C	Mapped by significant region
LAMA3	laminin, alpha 3	Mapped by significant region
COL8A1	collagen, type VIII, alpha 1	Mapped by CNV
MPZL3	myelin protein zero-like 3	Mapped by significant region
ASTL	astacin-like metallo-endopeptidase (M12 family)	Mapped by LD-proxy
CTNND1	catenin (cadherin-associated protein), delta 1	Mapped by significant region	NAS[8808291]
SCARB1	scavenger receptor class B, member 1	Mapped by CNV
FLRT1	fibronectin leucine rich transmembrane protein 1	Mapped by significant region
SORBS3	sorbin and SH3 domain containing 3	Mapped by PBA pathway	TAS[9885244]
STAB2	stabilin 2	Mapped by LD-proxy	NAS[12077138]
ROM1	retinal outer segment membrane protein 1	Mapped by significant region
DSC2	desmocollin 2	Mapped by significant region	TAS[2037591]
MCAM	melanoma cell adhesion molecule	Mapped by significant region
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region
SPECC1	sperm antigen with calponin homology and coiled-coil domains 1	Mapped by significant region
CTNNAL1	catenin (cadherin-associated protein), alpha-like 1	Mapped by significant region
NCAM1	neural cell adhesion molecule 1	Mapped by significant region	NAS[10770948]
NRXN2	neurexin 2	Mapped by significant region
NTM	neurotrimin	Mapped by significant region
HEPACAM	hepatic and glial cell adhesion molecule	Mapped by significant region
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	Mapped by CNV; Mapped by significant region	TAS[9545347]
LAMC2	laminin, gamma 2	Mapped by significant region
CNTNAP4	contactin associated protein-like 4	Mapped by significant region
OPCML	opioid binding protein/cell adhesion molecule-like	Mapped by LD-proxy; Mapped by significant region
CD6	CD6 molecule	Mapped by significant region
CXCL12	chemokine (C-X-C motif) ligand 12	Mapped by PBA pathway	TAS[10198043]
AMBP	alpha-1-microglobulin/bikunin precursor	Mapped by significant region	NAS[9570066]
DGCR6	DiGeorge syndrome critical region gene 6	Mapped by CNV	TAS[8733130]
AATF	apoptosis antagonizing transcription factor	Mapped by CNV
ARF6	ADP-ribosylation factor 6	Mapped by PBA pathway	TAS[10036235]
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	Mapped by significant region	TAS[9096408]
CDHR5	cadherin-related family member 5	Mapped by LD-proxy
DGCR2	DiGeorge syndrome critical region gene 2	Mapped by CNV
GP1BB	glycoprotein Ib (platelet), beta polypeptide	Mapped by CNV
ACHE	acetylcholinesterase	Mapped by PBA pathway	IDA[15454088]; TAS[11283752]
ARHGAP5	Rho GTPase activating protein 5	Mapped by significant region	TAS[8537347]
CD300A	CD300a molecule	Mapped by CNV
FN1	fibronectin 1	Mapped by significant region	NAS[1423622]
PERP	PERP, TP53 apoptosis effector	Mapped by significant region
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	Mapped by significant region	TAS[7743525]
CDH4	cadherin 4, type 1, R-cadherin (retinal)	Mapped by CNV	TAS[2059658]
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	Mapped by significant region	NAS[12764381]
DSG2	desmoglein 2	Mapped by significant region	IDA[17559062]
TNR	tenascin R (restrictin, janusin)	Mapped by significant region	NAS[8940128]
LPXN	leupaxin	Mapped by significant region
COL15A1	collagen, type XV, alpha 1	Mapped by significant region	IC[9651385]
OMD	osteomodulin	Mapped by significant region
INPPL1	inositol polyphosphate phosphatase-like 1	Mapped by significant region	TAS[15668240]
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	Mapped by CNV	TAS[9223106]
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	Mapped by significant region	TAS[8876214]
CDON	Cdon homolog (mouse)	Mapped by significant region	TAS[9214393]
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region	IDA[14970227]
APC	adenomatous polyposis coli	Mapped by LD-proxy; Mapped by PBA pathway	NAS[8259518]
CFDP1	craniofacial development protein 1	Mapped by significant region
MFAP4	microfibrillar-associated protein 4	Mapped by significant region
SDK1	sidekick homolog 1, cell adhesion molecule (chicken)	Mapped by CNV
CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)	Mapped by CNV
LAMA2	laminin, alpha 2	Mapped by CNV; Mapped by significant region
SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	Mapped by significant region
PDZD2	PDZ domain containing 2	Mapped by significant region
TGFB1I1	transforming growth factor beta 1 induced transcript 1	Mapped by PBA pathway	TAS[9422762]