ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007420
Name brain development
Type biological process
No. of Genes in ADHDgene  36
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 36)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MACROD2 MACRO domain containing 2 20p12.1 1(0/0/1) IEA
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1p36-p35 2(0/2/0) IEA
CADM2 cell adhesion molecule 2 3p12.2 1(1/0/0) IEA
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IEA
NTF3 neurotrophin 3 12p13 4(1/3/0) IEA
SNPH syntaphilin 20p13 1(1/0/0) IEA
CNTN4 contactin 4 3p26.3 1(1/0/0) ISS

Genes from other sources Help (count: 29)

Approved Symbol Approved Name Source Evidence[PMID]
PTCH1 patched 1 Mapped by significant region ISS
CADM1 cell adhesion molecule 1 Mapped by significant region IEA
FOXL1 forkhead box L1 Mapped by significant region IBA
OXCT1 3-oxoacid CoA transferase 1 Mapped by significant region IEA
CXCL12 chemokine (C-X-C motif) ligand 12 Mapped by PBA pathway IEA
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) Mapped by significant region IEA
MEN1 multiple endocrine neoplasia I Mapped by significant region IEA
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Mapped by CNV; Mapped by significant region IEA
SEPP1 selenoprotein P, plasma, 1 Mapped by CNV; Mapped by significant region IEA
STK36 serine/threonine kinase 36 Mapped by significant region IEA
INPPL1 inositol polyphosphate phosphatase-like 1 Mapped by significant region IEA
FZD4 frizzled class receptor 4 Mapped by significant region IBA
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 Mapped by significant region TAS[9245688]
DSCAML1 Down syndrome cell adhesion molecule like 1 Mapped by significant region IDA[12051741]
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region IEA
UBE3A ubiquitin protein ligase E3A Mapped by CNV; Mapped by significant region TAS[8988171]
CNTNAP2 contactin associated protein-like 2 Mapped by CNV TAS[10624965]
FOXG1 forkhead box G1 Mapped by significant region TAS[7599184]
NIPBL Nipped-B homolog (Drosophila) Mapped by significant region IMP[8291537]
C2CD3 C2 calcium-dependent domain containing 3 Mapped by significant region IEA
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 Mapped by significant region IMP
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha Mapped by PBA pathway IEA
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) Mapped by significant region IEA
ACAT1 acetyl-CoA acetyltransferase 1 Mapped by CNV; Mapped by significant region IEA
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IEA
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway ISS
BCL2L11 BCL2-like 11 (apoptosis facilitator) Mapped by LD-proxy IEA
MAP1S microtubule-associated protein 1S Mapped by PBA pathway ISS[15528209]
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region ISS; NAS[10915792]