ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0007193
Name	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	6
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 6)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
OPRM1	opioid receptor, mu 1	6q24-q25	1(1/0/0)
GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide	22q11.1-q11.2	1(0/1/0)
GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	18p11.22-p11.21	1(1/0/0)

Genes from other sources (count: 3)

Approved Symbol	Approved Name	Source	Evidence[PMID]
S1PR3	sphingosine-1-phosphate receptor 3	Mapped by significant region
NPR3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	Mapped by significant region
ADCY4	adenylate cyclase 4	Mapped by significant region