ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007193
Name adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  10
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 10)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
OPRM1 opioid receptor, mu 1 6q24-q25 1(1/0/0) IEA
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18p11.22-p11.21 1(1/0/0) TAS
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(0/1/0) IEA

Genes from other sources Help (count: 7)

Approved Symbol Approved Name Source Evidence[PMID]
NPR3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) Mapped by significant region IEA
ADCY3 adenylate cyclase 3 Mapped by LD-proxy TAS
ADCY9 adenylate cyclase 9 Mapped by significant region TAS
ADCY4 adenylate cyclase 4 Mapped by significant region TAS
ADCY2 adenylate cyclase 2 (brain) Mapped by significant region TAS
PTGDR2 prostaglandin D2 receptor 2 Mapped by significant region IEA
S1PR3 sphingosine-1-phosphate receptor 3 Mapped by significant region IEA