ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0015629
Name	actin cytoskeleton
Type	cellular component
No. of Genes in ADHDgene	30
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 30)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	4q21.3-q22	1(0/1/0)	IDA[17408955]
CTNNA2	catenin (cadherin-associated protein), alpha 2	2p12-p11.1	2(1/1/0)	IEA
BAIAP2	BAI1-associated protein 2	17q25	1(1/0/0)	IDA[19366662]
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	7p22	1(0/1/0)	IDA

Genes from other sources (count: 26)

Approved Symbol	Approved Name	Source	Evidence[PMID]
LIMA1	LIM domain and actin binding 1	Mapped by PBA pathway	IDA
CORO2A	coronin, actin binding protein, 2A	Mapped by significant region	IBA
FYB	FYN binding protein	Mapped by significant region	TAS[10747096]
ALDOA	aldolase A, fructose-bisphosphate	Mapped by CNV	IDA[9244396]
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region	IDA[17010968]
COPB2	coatomer protein complex, subunit beta 2 (beta prime)	Mapped by PBA pathway	IDA
CORO1B	coronin, actin binding protein, 1B	Mapped by significant region	IBA
TARS	threonyl-tRNA synthetase	Mapped by significant region	IDA
IQGAP2	IQ motif containing GTPase activating protein 2	Mapped by CNV	TAS[8756646]
PPP1R12B	protein phosphatase 1, regulatory subunit 12B	Mapped by Literature SNP	IDA
ARHGAP32	Rho GTPase activating protein 32	Mapped by significant region	IEA
GSN	gelsolin	Mapped by significant region; Mapped by PBA pathway	IEA
ZNF74	zinc finger protein 74	Mapped by CNV	IDA
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	Mapped by CNV	IDA
CORO7	coronin 7	Mapped by significant region	IRD
KLHL20	kelch-like family member 20	Mapped by significant region	TAS[10888605]
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	Mapped by significant region	TAS[9230079]
PKNOX2	PBX/knotted 1 homeobox 2	Mapped by significant region	IEA
ZNF174	zinc finger protein 174	Mapped by significant region	IDA
C10orf90	chromosome 10 open reading frame 90	Mapped by CNV	IDA
FMN1	formin 1	Mapped by CNV; Mapped by significant region	IEA
CTNNA3	catenin (cadherin-associated protein), alpha 3	Mapped by CNV	IEA
CTNNAL1	catenin (cadherin-associated protein), alpha-like 1	Mapped by significant region	IEA
WASL	Wiskott-Aldrich syndrome-like	Mapped by CNV	TAS[9422512]
ACTL7B	actin-like 7B	Mapped by significant region	TAS[10373328]
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	Mapped by significant region	TAS[9230079]