ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007219
Name Notch signaling pathway
Type biological process
No. of Genes in ADHDgene  23
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 23)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FURIN furin (paired basic amino acid cleaving enzyme) 15q26.1 1(0/0/1) TAS
ARRB1 arrestin, beta 1 11q13 2(1/1/0) TAS
ZNF423 zinc finger protein 423 16q12 1(0/0/1) ISS
ARRB2 arrestin, beta 2 17p13 1(1/0/0) TAS
TLE4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) TAS
HES1 hes family bHLH transcription factor 1 3q28-q29 1(1/0/0) IDA[16160079]; IMP[19682396]; TAS
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) TAS

Genes from other sources Help (count: 16)

Approved Symbol Approved Name Source Evidence[PMID]
ADAM17 ADAM metallopeptidase domain 17 Mapped by significant region IEA
MIB1 mindbomb E3 ubiquitin protein ligase 1 Mapped by significant region TAS
MAML2 mastermind-like 2 (Drosophila) Mapped by significant region IDA[12370315]; TAS
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) Mapped by significant region IBA
RBPJ recombination signal binding protein for immunoglobulin kappa J region Mapped by CNV IMP[18663143]; TAS
DTX4 deltex 4, E3 ubiquitin ligase Mapped by significant region IEA
MAML1 mastermind-like 1 (Drosophila) Mapped by CNV IDA[11101851]; TAS
UBB ubiquitin B Mapped by significant region TAS
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 Mapped by significant region ISS; TAS
EPN2 epsin 2 Mapped by significant region IEA
CNTN6 contactin 6 Mapped by CNV IEA
CREBBP CREB binding protein Mapped by significant region TAS
GMDS GDP-mannose 4,6-dehydratase Mapped by CNV ISS
NCOR2 nuclear receptor corepressor 2 Mapped by CNV TAS
UBC ubiquitin C Mapped by CNV TAS
SNW1 SNW domain containing 1 Mapped by PBA pathway TAS