ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0043154
Name negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Type biological process
No. of Genes in ADHDgene  12
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 12)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MAP2K5 mitogen-activated protein kinase kinase 5 15q22.31 1(1/0/0) ISS
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) IDA[18386220]
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IMP[10818098]
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) ISS

Genes from other sources Help (count: 8)

Approved Symbol Approved Name Source Evidence[PMID]
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IEA
PRDX5 peroxiredoxin 5 Mapped by significant region IMP[18262354]
KLF4 Kruppel-like factor 4 (gut) Mapped by significant region IDA
ADORA2A adenosine A2a receptor Mapped by CNV IEA
CRYAB crystallin, alpha B Mapped by significant region IEA
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 Mapped by significant region IDA[10411904]
DPEP1 dipeptidase 1 (renal) Mapped by significant region IMP
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 Mapped by significant region IDA[12167698]