ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0008233
Name peptidase activity
Type molecular function
No. of Genes in ADHDgene  17
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 17)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
QPCTL glutaminyl-peptide cyclotransferase-like 19q13.32 1(0/1/0) IEA
FURIN furin (paired basic amino acid cleaving enzyme) 15q26.1 1(0/0/1) IDA[15082773]

Genes from other sources Help (count: 15)

Approved Symbol Approved Name Source Evidence[PMID]
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 Mapped by significant region NAS[9388249]
TMPRSS11D transmembrane protease, serine 11D Mapped by significant region TAS[9565616]
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 Mapped by significant region IDA[18223652]
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 Mapped by CNV IEA
TMPRSS5 transmembrane protease, serine 5 Mapped by significant region IMP[17918732]
CTSG cathepsin G Mapped by significant region IDA[11907569]
CAPN15 calpain 15 Mapped by significant region TAS[9722942]
IHH indian hedgehog Mapped by significant region IEA
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) Mapped by CNV ISS[15814844]
SHFM1 split hand/foot malformation (ectrodactyly) type 1 Mapped by LD-proxy IDA[10373512]
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) Mapped by significant region TAS[9635427]
TPP1 tripeptidyl peptidase I Mapped by CNV IMP[9295267]
ASTL astacin-like metallo-endopeptidase (M12 family) Mapped by LD-proxy IDA[15087446]
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) Mapped by LD-proxy IEA
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) Mapped by significant region IEA