ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007271
Name synaptic transmission, cholinergic
Type biological process
No. of Genes in ADHDgene  8
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 8)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
BCHE butyrylcholinesterase 3q26.1-q26.2 1(1/0/0) IBA
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 15q24 1(0/1/0) ISS
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2q12 1(1/0/0) IEA
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 20q13.33 7(4/3/0) ISS

Genes from other sources Help (count: 4)

Approved Symbol Approved Name Source Evidence[PMID]
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) Mapped by LD-proxy TAS[1330682]
ADORA2A adenosine A2a receptor Mapped by CNV IEA
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IBA
RAPSN receptor-associated protein of the synapse Mapped by LD-proxy IGI[18420419]