ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006281
Name DNA repair
Type biological process
No. of Genes in ADHDgene  70
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 70)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FANCL Fanconi anemia, complementation group L 2p16.1 1(0/1/0) IMP[16916645]; TAS
CSNK1E casein kinase 1, epsilon 22q13.1 2(1/1/0) TAS[7797465]
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 20q13.33 7(4/3/0) IMP[16332175]

Genes from other sources Help (count: 67)

Approved Symbol Approved Name Source Evidence[PMID]
UBB ubiquitin B Mapped by significant region TAS
NDNL2 necdin-like 2 Mapped by CNV; Mapped by significant region IEA
RFWD3 ring finger and WD repeat domain 3 Mapped by significant region IEA
ERCC4 excision repair cross-complementing rodent repair deficiency, complementation group 4 Mapped by significant region IMP[19596235]; TAS
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 Mapped by significant region IEA
GADD45G growth arrest and DNA-damage-inducible, gamma Mapped by significant region TAS[9827804]
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region TAS
MUS81 MUS81 structure-specific endonuclease subunit Mapped by significant region IMP[19596235]
RBM14 RNA binding motif protein 14 Mapped by significant region NAS[11443112]
EYA4 eyes absent homolog 4 (Drosophila) Mapped by significant region IEA
PTTG1 pituitary tumor-transforming 1 Mapped by significant region IEA
XPA xeroderma pigmentosum, complementation group A Mapped by significant region TAS
FEN1 flap structure-specific endonuclease 1 Mapped by Literature SNP; Mapped by significant region NAS[15504738]; TAS
UBC ubiquitin C Mapped by CNV TAS
RBBP8 retinoblastoma binding protein 8 Mapped by significant region TAS[10764811]
RAD1 RAD1 homolog (S. pombe) Mapped by significant region IEA
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region TAS
ERCC8 excision repair cross-complementing rodent repair deficiency, complementation group 8 Mapped by CNV TAS
ERCC6L2 excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2 Mapped by significant region IEA
ASF1A anti-silencing function 1A histone chaperone Mapped by significant region IDA[11897662]
SSRP1 structure specific recognition protein 1 Mapped by significant region IEA
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region TAS
INO80E INO80 complex subunit E Mapped by CNV IEA
UVRAG UV radiation resistance associated Mapped by significant region TAS[9169138]
NFRKB nuclear factor related to kappaB binding protein Mapped by significant region IEA
MEN1 multiple endocrine neoplasia I Mapped by significant region NAS[12874027]
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway NAS[11443112]
FAN1 FANCD2/FANCI-associated nuclease 1 Mapped by CNV; Mapped by significant region IMP
POLD3 polymerase (DNA-directed), delta 3, accessory subunit Mapped by significant region TAS
USP28 ubiquitin specific peptidase 28 Mapped by significant region IEA
DDB1 damage-specific DNA binding protein 1, 127kDa Mapped by significant region TAS
CHD1L chromodomain helicase DNA binding protein 1-like Mapped by CNV TAS[19661379]
SMC2 structural maintenance of chromosomes 2 Mapped by significant region IEA
H2AFX H2A histone family, member X Mapped by significant region TAS
CHEK1 checkpoint kinase 1 Mapped by significant region IMP[19716789]
PALB2 partner and localizer of BRCA2 Mapped by significant region TAS
USP10 ubiquitin specific peptidase 10 Mapped by CNV; Mapped by significant region IEA
RAD23B RAD23 homolog B (S. cerevisiae) Mapped by significant region TAS
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase Mapped by significant region IEA
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) Mapped by CNV IMP[19596236]
SMC1A structural maintenance of chromosomes 1A Mapped by PBA pathway TAS[11877377]
CDC14B cell division cycle 14B Mapped by significant region IEA
SLX4 SLX4 structure-specific endonuclease subunit Mapped by significant region IMP[19595722]
INO80C INO80 complex subunit C Mapped by significant region IEA
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Mapped by significant region IEA
FANCA Fanconi anemia, complementation group A Mapped by significant region TAS
NTHL1 nth endonuclease III-like 1 (E. coli) Mapped by significant region TAS
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 Mapped by significant region IDA
MPG N-methylpurine-DNA glycosylase Mapped by significant region TAS
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa Mapped by CNV TAS
INIP INTS3 and NABP interacting protein Mapped by significant region IMP[19605351]
FANCC Fanconi anemia, complementation group C Mapped by significant region TAS
POLD4 polymerase (DNA-directed), delta 4, accessory subunit Mapped by significant region TAS
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region IEA
BARD1 BRCA1 associated RING domain 1 Mapped by significant region IEA
C11orf30 chromosome 11 open reading frame 30 Mapped by significant region IEA
POLR2G polymerase (RNA) II (DNA directed) polypeptide G Mapped by significant region TAS
HINFP histone H4 transcription factor Mapped by significant region IMP[17974976]
EME2 essential meiotic structure-specific endonuclease subunit 2 Mapped by significant region IEA
IGHMBP2 immunoglobulin mu binding protein 2 Mapped by CNV; Mapped by significant region TAS[8493094]
CEP164 centrosomal protein 164kDa Mapped by significant region IEA
KIF22 kinesin family member 22 Mapped by CNV IEA
PRPF19 pre-mRNA processing factor 19 Mapped by significant region IEA
SMC3 structural maintenance of chromosomes 3 Mapped by PBA pathway IEA
TRIP12 thyroid hormone receptor interactor 12 Mapped by PBA pathway IEA
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) Mapped by PBA pathway IMP
TP53BP1 tumor protein p53 binding protein 1 Mapped by Literature SNP TAS