ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006281
Name DNA repair
Type Biological Process
No. of Genes in ADHDgene  62
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 62)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
CHRNA4 cholinergic receptor, nicotinic, alpha 4 20 7(4/3/0) IMP[16332175]
CSNK1E casein kinase 1, epsilon 22q13.1 2(1/1/0) TAS[7797465]

Genes from other sources Help (count: 60)

Approved Symbol Approved Name Source Evidence[PMID]
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa Mapped by CNV
INO80E INO80 complex subunit E Mapped by CNV
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) Mapped by PBA pathway
INO80C INO80 complex subunit C Mapped by significant region
HERC2 hect domain and RLD 2 Mapped by significant region
IGHMBP2 immunoglobulin mu binding protein 2 Mapped by CNV; Mapped by significant region TAS[8493094]
FAN1 FANCD2/FANCI-associated nuclease 1 Mapped by CNV; Mapped by significant region
POLD4 polymerase (DNA-directed), delta 4 Mapped by significant region
RAD23B RAD23 homolog B (S. cerevisiae) Mapped by significant region
SMC3 structural maintenance of chromosomes 3 Mapped by PBA pathway
CEP164 centrosomal protein 164kDa Mapped by significant region
MUS81 MUS81 endonuclease homolog (S. cerevisiae) Mapped by significant region IMP[19596235]
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) Mapped by CNV IMP[19596236]
TP53BP1 tumor protein p53 binding protein 1 Mapped by LD-proxy; Mapped by literature SNP
POLE polymerase (DNA directed), epsilon Mapped by CNV
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region
FANCC Fanconi anemia, complementation group C Mapped by significant region
UBB ubiquitin B Mapped by significant region
ERCC8 excision repair cross-complementing rodent repair deficiency, complementation group 8 Mapped by CNV
PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) Mapped by significant region
USP10 ubiquitin specific peptidase 10 Mapped by CNV; Mapped by significant region
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region
MEN1 multiple endocrine neoplasia I Mapped by significant region NAS[12874027]
RBM14 RNA binding motif protein 14 Mapped by significant region NAS[11443112]
C11orf30 chromosome 11 open reading frame 30 Mapped by significant region
CHD1L chromodomain helicase DNA binding protein 1-like Mapped by CNV TAS[19661379]
SMG1 smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) Mapped by significant region
H2AFX H2A histone family, member X Mapped by significant region
FANCA Fanconi anemia, complementation group A Mapped by significant region
POLR2G polymerase (RNA) II (DNA directed) polypeptide G Mapped by significant region
HINFP histone H4 transcription factor Mapped by significant region IMP[17974976]
RAD1 RAD1 homolog (S. pombe) Mapped by significant region
UVRAG UV radiation resistance associated gene Mapped by significant region TAS[9169138]
ASF1A ASF1 anti-silencing function 1 homolog A (S. cerevisiae) Mapped by significant region IDA[11897662]
TRIP12 thyroid hormone receptor interactor 12 Mapped by PBA pathway
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway NAS[11443112]
SMC1A structural maintenance of chromosomes 1A Mapped by PBA pathway TAS[11877377]
CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) Mapped by significant region
PTTG1 pituitary tumor-transforming 1 Mapped by significant region
PALB2 partner and localizer of BRCA2 Mapped by significant region
RBBP8 retinoblastoma binding protein 8 Mapped by significant region TAS[10764811]
NFRKB nuclear factor related to kappaB binding protein Mapped by significant region
RFWD3 ring finger and WD repeat domain 3 Mapped by significant region
CHEK1 CHK1 checkpoint homolog (S. pombe) Mapped by significant region IMP[19716789]
UBC ubiquitin C Mapped by CNV
EYA4 eyes absent homolog 4 (Drosophila) Mapped by significant region
OTUB1 OTU domain, ubiquitin aldehyde binding 1 Mapped by significant region
POLD3 polymerase (DNA-directed), delta 3, accessory subunit Mapped by significant region
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region
BARD1 BRCA1 associated RING domain 1 Mapped by significant region
DDB1 damage-specific DNA binding protein 1, 127kDa Mapped by significant region
GADD45G growth arrest and DNA-damage-inducible, gamma Mapped by significant region TAS[9827804]
SSRP1 structure specific recognition protein 1 Mapped by significant region
SMC2 structural maintenance of chromosomes 2 Mapped by significant region
XPA xeroderma pigmentosum, complementation group A Mapped by significant region
USP28 ubiquitin specific peptidase 28 Mapped by significant region
FEN1 flap structure-specific endonuclease 1 Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region NAS[15504738]
KIF22 kinesin family member 22 Mapped by CNV
NDNL2 necdin-like 2 Mapped by CNV; Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014