ADHDgene Database

Gene Report

Basic Info

Approved Symbol	UCP2
Symbol Alias	SLC25A8
Approved Name	uncoupling protein 2 (mitochondrial, proton carrier)
Location	11q13
Position	chr11:73685716-73693889, -
External Links	HGNC: 12518 Entrez Gene: 7351 Ensembl: ENSG00000175567 UCSC: uc001oup.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Lesch[2011]_7	chr11:72900000-73400000 (NCBI Build 35 (hg17))	500000	11q13.4	Duplication	Maternal (affected, also in affected sibling)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0070542	response to fatty acid	Biological Process		3
GO:0022904	respiratory electron transport chain	Biological Process		15
GO:0032869	cellular response to insulin stimulus	Biological Process		7
GO:0015992	proton transport	Biological Process		6
GO:0016021	integral to membrane	Cellular Component		845
GO:0006839	mitochondrial transport	Biological Process		3
GO:0009749	response to glucose stimulus	Biological Process		10
GO:0005743	mitochondrial inner membrane	Cellular Component		44
GO:0006810	transport	Biological Process	NAS[9196039]	62
GO:0000303	response to superoxide	Biological Process		2
GO:0001666	response to hypoxia	Biological Process		34

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with UCP2 (count: 1)

Gene Symbol	Pathway Count	Pathway List
UCP3	8	small molecule metabolic process; respiratory electron transport chain; proton transport; integral to membrane; mitochondrial transport; mitochondrial inner membrane; response to superoxide; response to hypoxia;

Genes shared at least 2 KEGG pathways with UCP2 (count: 0)

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Region: chr11:73685716..73693889 View in gBrowse