ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TRPC4
Symbol Alias	HTRP4, TRP4
Approved Name	transient receptor potential cation channel, subfamily C, member 4
Location	13q13.3
Position	chr13:38210773-38444562, -
External Links	HGNC: 12336 Entrez Gene: 7223 Ensembl: ENSG00000133107 UCSC: uc010abx.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005262	calcium channel activity	Molecular Function		40

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005515	protein binding	Molecular Function	IPI[15757897]	910
GO:0005886	plasma membrane	Cellular Component	IDA[16254212]	772
GO:0006816	calcium ion transport	Biological Process	TAS[8646775]	32
GO:0007411	axon guidance	Biological Process		65
GO:0005901	caveola	Cellular Component		12
GO:0005911	cell-cell junction	Cellular Component	IDA[19996314]	20
GO:0014051	gamma-aminobutyric acid secretion	Biological Process		2
GO:0015279	store-operated calcium channel activity	Molecular Function	IMP[16254212]	7
GO:0008013	beta-catenin binding	Molecular Function	IPI[19996314]	10
GO:0009986	cell surface	Cellular Component	IDA[19996314]	70
GO:0030863	cortical cytoskeleton	Cellular Component	IDA[16254212]	2
GO:0016323	basolateral plasma membrane	Cellular Component	IDA[19996314]	29
GO:0045296	cadherin binding	Molecular Function	IPI[19996314]	9
GO:0034704	calcium channel complex	Cellular Component		4
GO:0070679	inositol 1,4,5 trisphosphate binding	Molecular Function		5
GO:0070509	calcium ion import	Biological Process	IDA[19996314]	6

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TRPC4 (count: 10)

Gene Symbol	Pathway Count	Pathway List
TRPC1	8	protein binding; plasma membrane; calcium channel activity; calcium ion transport; axon guidance; store-operated calcium channel activity; basolateral plasma membrane; inositol 1,4,5 trisphosphate binding;
TRPC3	7	protein binding; plasma membrane; calcium channel activity; calcium ion transport; axon guidance; store-operated calcium channel activity; inositol 1,4,5 trisphosphate binding;
TRPC5	7	protein binding; calcium channel activity; calcium ion transport; axon guidance; store-operated calcium channel activity; calcium channel complex; inositol 1,4,5 trisphosphate binding;
ANK3	6	protein binding; plasma membrane; axon guidance; cell surface; basolateral plasma membrane; cadherin binding;
CACNB2	5	protein binding; calcium channel activity; calcium ion transport; axon guidance; calcium ion import;
CACNB4	5	protein binding; plasma membrane; calcium channel activity; axon guidance; gamma-aminobutyric acid secretion;
PTPRJ	5	protein binding; plasma membrane; cell-cell junction; beta-catenin binding; cell surface;
RYR2	5	protein binding; plasma membrane; calcium channel activity; calcium ion transport; calcium channel complex;
TRPC6	5	protein binding; plasma membrane; axon guidance; store-operated calcium channel activity; inositol 1,4,5 trisphosphate binding;
CACNA1D	5	plasma membrane; calcium channel activity; calcium ion transport; axon guidance; calcium ion import;

Genes shared at least 2 KEGG pathways with TRPC4 (count: 0)

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Region: chr13:38210773..38444562 View in gBrowse