ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SLX1A
Previous Symbol	GIYD1
Approved Name	SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
Previous Name	GIY-YIG domain containing 1
Location	16p11.2
Position	chr16:30205217-30208882, +
External Links	HGNC: 20922 Entrez Gene: 548593 Ensembl: ENSG00000132207
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 3)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_16	chr16:29563594-30367556 (NCBI Build 36.1 (hg18))	803963	16p11.2	Loss
CNV_Williams[2010]_34	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813248	16p11.2	Loss	De novo
CNV_Williams[2010]_39	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813247	16p11.2	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing	Biological Process	IMP[19595721]	2
GO:0008821	crossover junction endodeoxyribonuclease activity	Molecular Function	IDA[19596235]	1
GO:0033557	Slx1-Slx4 complex	Cellular Component	IDA[19596235]	1
GO:0017108	5'-flap endonuclease activity	Molecular Function	IDA[19596235]	3
GO:0000724	double-strand break repair via homologous recombination	Biological Process	IMP[19595721]	12
GO:0006281	DNA repair	Biological Process	IMP[19596236]	62
GO:0005515	protein binding	Molecular Function	IPI[19596236]	910
GO:0046872	metal ion binding	Molecular Function		170

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SLX1A (count: 0)

Genes shared at least 2 KEGG pathways with SLX1A (count: 0)

View in gBrowse

Region: chr16:30205217..30208882 View in gBrowse