ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RPL27A
Symbol Alias	L27A
Approved Name	ribosomal protein L27a
Location	11p15
Position	chr11:8703958-8736306, 1
External Links	HGNC: 10329 Entrez Gene: 6157 Ensembl: ENSG00000166441 UCSC: uc001mgs.4
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Albayrak O., 2013	No significant association was reported in this study.	Non-significant

Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs4929949	chr11:8604593(Fwd)	intron_variant; nc_transcript_variant	1(0/1/0)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0003723	RNA binding	molecular function	TAS[7772601]	115
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	biological process	TAS	23
GO:0022625	cytosolic large ribosomal subunit	cellular component	IDA[12962325]	9
GO:0019083	viral transcription	biological process	TAS	17
GO:0044267	cellular protein metabolic process	biological process	TAS	78
GO:0016070	RNA metabolic process	biological process	TAS	54
GO:0016071	mRNA metabolic process	biological process	TAS	41
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	biological process	TAS	23
GO:0006414	translational elongation	biological process	TAS	21
GO:0006413	translational initiation	biological process	TAS	19
GO:0005829	cytosol	cellular component	TAS	485
GO:0016032	viral reproduction	biological process	TAS	66
GO:0019058	viral infectious cycle	biological process	TAS	19
GO:0003735	structural constituent of ribosome	molecular function	NAS[12962325]	29
GO:0005515	protein binding	molecular function	IPI	1015
GO:0006412	translation	biological process	NAS[12962325]; TAS	49
GO:0006415	translational termination	biological process	TAS	17
GO:0010467	gene expression	biological process	TAS	154

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03010	Ribosome	17

Genes shared at least 5 GO terms with RPL27A (count: 47)

Gene Symbol	Pathway Count	Pathway List
RPL14	18	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytosolic large ribosomal subunit; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; protein binding; translation; translational termination; gene expression;
RPL13	18	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytosolic large ribosomal subunit; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; protein binding; translation; translational termination; gene expression;
RPS2	17	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; protein binding; translation; translational termination; gene expression;
RPL38	17	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytosolic large ribosomal subunit; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
RPL12	17	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytosolic large ribosomal subunit; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
RPL37	17	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytosolic large ribosomal subunit; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
RPL3L	17	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytosolic large ribosomal subunit; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
FAU	16	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
RPS15A	16	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
RPS25	16	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
RPS9	16	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; protein binding; translation; translational termination; gene expression;
RPL35	16	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytosolic large ribosomal subunit; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
RPS3	16	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; protein binding; translation; translational termination; gene expression;
RPL37A	16	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cytosolic large ribosomal subunit; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
RPS10	15	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; protein binding; translation; translational termination; gene expression;
RPS12	15	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; viral transcription; cellular protein metabolic process; RNA metabolic process; mRNA metabolic process; SRP-dependent cotranslational protein targeting to membrane; translational elongation; translational initiation; cytosol; viral reproduction; viral infectious cycle; structural constituent of ribosome; translation; translational termination; gene expression;
XPO1	8	RNA binding; RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; viral infectious cycle; protein binding; gene expression;
NCBP1	8	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; protein binding; gene expression;
PAIP1	7	RNA binding; RNA metabolic process; mRNA metabolic process; translational initiation; cytosol; protein binding; gene expression;
RNPS1	7	RNA binding; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
CNOT6	6	RNA binding; RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
LSM4	6	RNA binding; RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
DDX6	6	RNA binding; RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
PATL1	6	RNA binding; RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
SMG1	6	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
SMG7	6	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
PARN	6	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
EEF1D	6	cellular protein metabolic process; translational elongation; cytosol; protein binding; translation; gene expression;
EIF2B1	6	cellular protein metabolic process; translational initiation; cytosol; protein binding; translation; gene expression;
EEF1G	6	cellular protein metabolic process; translational elongation; cytosol; protein binding; translation; gene expression;
UBC	6	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; protein binding; gene expression;
PSMC3	6	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; protein binding; gene expression;
UBB	6	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; protein binding; gene expression;
PSMD7	6	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; protein binding; gene expression;
PSMD5	6	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; protein binding; gene expression;
PSMB7	6	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; protein binding; gene expression;
SNRPG	5	RNA binding; RNA metabolic process; cytosol; protein binding; gene expression;
SNRPD1	5	RNA binding; RNA metabolic process; cytosol; protein binding; gene expression;
SEC61B	5	cellular protein metabolic process; SRP-dependent cotranslational protein targeting to membrane; protein binding; translation; gene expression;
SRP19	5	cellular protein metabolic process; SRP-dependent cotranslational protein targeting to membrane; cytosol; translation; gene expression;
PSMA8	5	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; gene expression;
PSME1	5	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; gene expression;
PSME2	5	RNA metabolic process; mRNA metabolic process; cytosol; viral reproduction; gene expression;
DCPS	5	RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
HSPA8	5	RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
RQCD1	5	RNA metabolic process; mRNA metabolic process; cytosol; protein binding; gene expression;
RAN	5	cytosol; viral reproduction; viral infectious cycle; protein binding; gene expression;

Genes shared at least 2 KEGG pathways with RPL27A (count: 0)

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Region: chr11:8703958..8736306 View in gBrowse