ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RGS11
Approved Name	regulator of G-protein signaling 11
Previous Name	"regulator of G-protein signalling 11"
Location	16p13.3
Position	chr16:318300-325980, -1
External Links	HGNC: 9993 Entrez Gene: 8786 Ensembl: ENSG00000076344 UCSC: uc002cgj.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16p13	chr16:0-16800000	3 (2/1/0)
16p13.3	chr16:0-7900000	1 (1/0/0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005737	cytoplasm	cellular component	IBA	781
GO:0007186	G-protein coupled receptor signaling pathway	biological process	IEA	77
GO:0043234	protein complex	cellular component	IDA[18468998]	47
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	biological process	TAS[9789084]	6
GO:0005096	GTPase activator activity	molecular function	IBA	28
GO:0035556	intracellular signal transduction	biological process	IEA	52
GO:0004871	signal transducer activity	molecular function	IEA	56
GO:0038032	termination of G-protein coupled receptor signaling pathway	biological process	IEA	11
GO:0043547	positive regulation of GTPase activity	biological process	IBA; TAS[9789084]	12
GO:0005834	heterotrimeric G-protein complex	cellular component	IEA	9
GO:0044292	dendrite terminus	cellular component	IEA	1
GO:0005886	plasma membrane	cellular component	IBA	839

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RGS11 (count: 6)

Gene Symbol	Pathway Count	Pathway List
RGS16	6	cytoplasm; regulation of G-protein coupled receptor protein signaling pathway; GTPase activator activity; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity; plasma membrane;
AXIN1	6	cytoplasm; GTPase activator activity; signal transducer activity; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity; plasma membrane;
RGS3	6	cytoplasm; regulation of G-protein coupled receptor protein signaling pathway; GTPase activator activity; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity; plasma membrane;
ARRB1	5	cytoplasm; GTPase activator activity; positive regulation of GTPase activity; heterotrimeric G-protein complex; plasma membrane;
RGS18	5	cytoplasm; G-protein coupled receptor signaling pathway; GTPase activator activity; termination of G-protein coupled receptor signaling pathway; plasma membrane;
RGS8	5	cytoplasm; GTPase activator activity; termination of G-protein coupled receptor signaling pathway; positive regulation of GTPase activity; plasma membrane;

Genes shared at least 2 KEGG pathways with RGS11 (count: 0)

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Region: chr16:318300..325980 View in gBrowse