ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PHOX2A
Previous Symbol	ARIX, FEOM2
Symbol Alias	PMX2A, CFEOM2
Approved Name	paired-like homeobox 2a
Previous Name	aristaless (Drosophila) homeobox, aristaless homeobox (Drosophila), fibrosis of extraocular muscles, congenital, 2, autosomal recessive, "paired-like (aristaless) homeobox 2a"
Location	11q13.4
Position	chr11:71950121-71955220, -
External Links	HGNC: 691 Entrez Gene: 401 Ensembl: ENSG00000165462 UCSC: uc001osh.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0071542	dopaminergic neuron differentiation	Biological Process	IC[19573018]	3
GO:0048485	sympathetic nervous system development	Biological Process		5
GO:0030901	midbrain development	Biological Process		5
GO:0021703	locus ceruleus development	Biological Process		1
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[16280598]; IMP[19573018]	131
GO:0043576	regulation of respiratory gaseous exchange	Biological Process		2
GO:0021623	oculomotor nerve formation	Biological Process		2
GO:0021642	trochlear nerve formation	Biological Process		1
GO:0006351	transcription, DNA-dependent	Biological Process		247
GO:0021523	somatic motor neuron differentiation	Biological Process		1
GO:0003357	noradrenergic neuron differentiation	Biological Process	IC[19573018]; NAS[16280598]	1
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function		132
GO:0000790	nuclear chromatin	Cellular Component	IDA[16280598]	11
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	Molecular Function	IDA[16280598]	3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PHOX2A (count: 0)

Genes shared at least 2 KEGG pathways with PHOX2A (count: 0)

View in gBrowse

Region: chr11:71950121..71955220 View in gBrowse