ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	PEX7
Symbol Alias	PTS2R, RD
Approved Name	peroxisomal biogenesis factor 7
Name Alias	"Refsum disease"
Location	6q21-q22.2
Position	chr6:137143717-137235075, 1
External Links	HGNC: 8860 Entrez Gene: 5191 Ensembl: ENSG00000112357 UCSC: uc003qhd.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by Literature SNP; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 33)

Literature-origin SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs6919857	chr6:137140454(Fwd)	upstream_gene_variant	2(0/2/0)

LD-proxies (count: 32)

rs_ID	Location	Functional Annotation
rs9399197	chr6:137164798(Fwd)	intron_variant
rs2012700	chr6:137179387(Fwd)	intron_variant; upstream_gene_variant
rs717088	chr6:137179449(Fwd)	intron_variant; upstream_gene_variant
rs9373174	chr6:137185164(Fwd)	intron_variant
rs1474987	chr6:137185293(Fwd)	intron_variant
rs1884940	chr6:137187641(Fwd)	intron_variant
rs9321578	chr6:137188609(Fwd)	intron_variant
rs6936400	chr6:137206262(Fwd)	intron_variant
rs3757169	chr6:137142946(Fwd)	upstream_gene_variant
rs7764028	chr6:137150543(Fwd)	intron_variant
rs9494579	chr6:137153974(Fwd)	downstream_gene_variant; intron_variant
rs6570104	chr6:137154620(Fwd)	downstream_gene_variant; intron_variant
rs1321473	chr6:137158764(Fwd)	intron_variant
rs6939424	chr6:137160983(Fwd)	intron_variant
rs7740484	chr6:137161671(Fwd)	intron_variant
rs9402850	chr6:137164622(Fwd)	intron_variant
rs7750763	chr6:137204016(Fwd)	intron_variant
rs7750251	chr6:137203746(Fwd)	intron_variant
rs1342644	chr6:137206928(Fwd)	intron_variant
rs9321580	chr6:137204280(Fwd)	intron_variant
rs9321582	chr6:137218692(Fwd)	downstream_gene_variant; intron_variant
rs9321581	chr6:137209311(Fwd)	intron_variant
rs1342645	chr6:137207304(Fwd)	intron_variant
rs3799476	chr6:137184073(Fwd)	intron_variant
rs927182	chr6:137162299(Fwd)	intron_variant
rs1884939	chr6:137187606(Fwd)	intron_variant
rs9494587	chr6:137184492(Fwd)	intron_variant
rs9494591	chr6:137196695(Fwd)	intron_variant
rs2050713	chr6:137194033(Fwd)	intron_variant
rs3757167	chr6:137140993(Fwd)	upstream_gene_variant
rs1998164	chr6:137140077(Fwd)	upstream_gene_variant
rs1321469	chr6:137139518(Fwd)	upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006635	fatty acid beta-oxidation	biological process	IEA	5
GO:0008611	ether lipid biosynthetic process	biological process	IMP[12522768]	1
GO:0042803	protein homodimerization activity	molecular function	IDA[11931631]	128
GO:0007031	peroxisome organization	biological process	IMP[10022913]	3
GO:0005777	peroxisome	cellular component	IDA[9090382]	17
GO:0016558	protein import into peroxisome matrix	biological process	IDA[9090381]; IMP[12522768]	3
GO:0001764	neuron migration	biological process	IEA	22
GO:0005829	cytosol	cellular component	IDA[11931631]	485
GO:0019899	enzyme binding	molecular function	IPI[11931631]	54
GO:0001958	endochondral ossification	biological process	IEA	1
GO:0005782	peroxisomal matrix	cellular component	IDA[11931631]	5
GO:0005053	peroxisome matrix targeting signal-2 binding	molecular function	IDA[11931631]	2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PEX7 (count: 0)

Genes shared at least 2 KEGG pathways with PEX7 (count: 0)

View in gBrowse

Region: chr6:137143717..137235075 View in gBrowse