ADHDgene Database

Gene Report

Basic Info

Approved Symbol	OTUB1
Symbol Alias	FLJ20113, FLJ40710
Approved Name	OTU domain, ubiquitin aldehyde binding 1
Location	11q13.1
Position	chr11:63753325-63765892, +
External Links	HGNC: 23077 Entrez Gene: 55611 Ensembl: ENSG00000167770 UCSC: uc001nyf.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005737	cytoplasm	Cellular Component		690
GO:0005515	protein binding	Molecular Function	IPI[19615732]	910
GO:0006508	proteolysis	Biological Process		102
GO:0006281	DNA repair	Biological Process		62
GO:0008242	omega peptidase activity	Molecular Function		1
GO:0006974	response to DNA damage stimulus	Biological Process		37
GO:0031625	ubiquitin protein ligase binding	Molecular Function		23
GO:0019784	NEDD8-specific protease activity	Molecular Function	IDA[18954305]	1
GO:0071108	protein K48-linked deubiquitination	Biological Process	IDA[19211026]	3
GO:0043130	ubiquitin binding	Molecular Function	IDA[19211026]	9
GO:2000780	negative regulation of double-strand break repair	Biological Process		3
GO:1901315	negative regulation of histone H2A K63-linked ubiquitination	Biological Process		2
GO:0004843	ubiquitin-specific protease activity	Molecular Function	IDA[19211026]	9

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with OTUB1 (count: 3)

Gene Symbol	Pathway Count	Pathway List
TRIP12	6	cytoplasm; protein binding; DNA repair; response to DNA damage stimulus; negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination;
HERC2	5	cytoplasm; protein binding; DNA repair; response to DNA damage stimulus; ubiquitin protein ligase binding;
TNFAIP3	5	cytoplasm; protein binding; proteolysis; ubiquitin binding; ubiquitin-specific protease activity;

Genes shared at least 2 KEGG pathways with OTUB1 (count: 0)

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Region: chr11:63753325..63765892 View in gBrowse