ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NSMCE2
Previous Symbol	C8orf36
Symbol Alias	FLJ32440, MMS21, NSE2
Approved Name	non-SMC element 2, MMS21 homolog (S. cerevisiae)
Previous Name	chromosome 8 open reading frame 36, "non-SMC element 2 homolog (MMS21, S. cerevisiae)"
Location	8q24.13
Position	chr8:126103921-126379367, +
External Links	HGNC: 26513 Entrez Gene: 286053 Ensembl: ENSG00000156831 UCSC: uc003yrw.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_105	chr8:126101864-126419388 (NCBI Build 35 (hg17))	317525	8q24.13	Duplication	Maternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0090398	cellular senescence	Biological Process	IMP[17589526]	3
GO:0051301	cell division	Biological Process		58
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	Biological Process	IMP[19502785]	1
GO:0034184	positive regulation of maintenance of mitotic sister chromatid cohesion	Biological Process	IMP[19502785]	1
GO:0030915	Smc5-Smc6 complex	Cellular Component	IDA[18086888]	2
GO:0019789	SUMO ligase activity	Molecular Function	IDA[17589526]	1
GO:0016925	protein sumoylation	Biological Process		2
GO:0016605	PML body	Cellular Component	IDA[17589526]	10
GO:0005515	protein binding	Molecular Function	IPI[18086888]	910
GO:0006303	double-strand break repair via nonhomologous end joining	Biological Process	IMP[16810316]	4
GO:0007067	mitosis	Biological Process		39
GO:0008270	zinc ion binding	Molecular Function		323
GO:0000722	telomere maintenance via recombination	Biological Process	IMP[17589526]	6
GO:0000724	double-strand break repair via homologous recombination	Biological Process	IMP[16810316]	12
GO:0000781	chromosome, telomeric region	Cellular Component	IDA[17589526]	9

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NSMCE2 (count: 0)

Genes shared at least 2 KEGG pathways with NSMCE2 (count: 0)

View in gBrowse

Region: chr8:126103921..126379367 View in gBrowse