ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NKX6-2
Symbol Alias	NKX6B, GTX, NKX6.1
Approved Name	NK6 homeobox 2
Previous Name	NK6 transcription factor related, locus 2 (Drosophila)
Location	10q26.3
Position	chr10:134598300-134599556, -
External Links	HGNC: 19321 Entrez Gene: 84504 Ensembl: ENSG00000148826 UCSC: uc001llr.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_23	chr10:132453545-135284293 (NCBI36 / hg18)	2830749	10q26.3	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0050885	neuromuscular process controlling balance	Biological Process		8
GO:0045687	positive regulation of glial cell differentiation	Biological Process		2
GO:0045686	negative regulation of glial cell differentiation	Biological Process		1
GO:0031018	endocrine pancreas development	Biological Process		7
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process		78
GO:0000976	transcription regulatory region sequence-specific DNA binding	Molecular Function		4
GO:0003700	sequence-specific DNA binding transcription factor activity	Molecular Function	NAS[11210186]	132
GO:0005634	nucleus	Cellular Component	NAS[11210186]	770
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	NAS[11210186]	158
GO:0010454	negative regulation of cell fate commitment	Biological Process		1
GO:0010455	positive regulation of cell fate commitment	Biological Process		1
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	Biological Process		1
GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	Biological Process		2
GO:0022010	central nervous system myelination	Biological Process		1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with NKX6-2 (count: 0)

Genes shared at least 2 KEGG pathways with NKX6-2 (count: 0)

View in gBrowse

Region: chr10:134598300..134599556 View in gBrowse