ADHDgene Database

Gene Report

Basic Info

Approved Symbol	HPX
Approved Name	hemopexin
Location	11p15.5-p15.4
Position	chr11:6452268-6463847, -
External Links	HGNC: 5171 Entrez Gene: 3263 Ensembl: ENSG00000110169 UCSC: uc001mdg.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_29	chr11:5582423-7488751 (NCBI Build 36.1 (hg18))	1859865	11p15.4	Loss	De novo

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0015232	heme transporter activity	Molecular Function	TAS[3855550]	3
GO:0006879	cellular iron ion homeostasis	Biological Process	TAS[3855550]	12
GO:0019048	virus-host interaction	Biological Process		54
GO:0015886	heme transport	Biological Process	TAS[3855550]	3
GO:0005515	protein binding	Molecular Function		910
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	Biological Process		1
GO:0005615	extracellular space	Cellular Component	IDA[19433579]	126
GO:0005576	extracellular region	Cellular Component	NAS[14718574]	240
GO:0060335	positive regulation of interferon-gamma-mediated signaling pathway	Biological Process		2
GO:0042168	heme metabolic process	Biological Process		1
GO:0020027	hemoglobin metabolic process	Biological Process		1
GO:0046872	metal ion binding	Molecular Function		170
GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein	Biological Process		1
GO:0002639	positive regulation of immunoglobulin production	Biological Process		3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with HPX (count: 0)

Genes shared at least 2 KEGG pathways with HPX (count: 0)

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Region: chr11:6452268..6463847 View in gBrowse