ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GPNMB
Symbol Alias	NMB, HGFIN
Approved Name	glycoprotein (transmembrane) nmb
Name Alias	transmembrane glycoprotein, "glycoprotein NMB", "glycoprotein nmb-like protein", "osteoactivin"
Location	7p
Position	chr7:23275586-23314729, +
External Links	HGNC: 4462 Entrez Gene: 10457 Ensembl: ENSG00000136235 UCSC: uc003swb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Lesch[2011]_6	chr7:23010000-26070000 (NCBI Build 35 (hg17))	3060000	7p15.2-7p15.3	Duplication	Paternal (affected)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
7p15	chr7:20900000-28800000	2 (1/1/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007155	cell adhesion	Biological Process		86
GO:0008201	heparin binding	Molecular Function		26
GO:0005178	integrin binding	Molecular Function		15
GO:0005887	integral to plasma membrane	Cellular Component		220
GO:0001649	osteoblast differentiation	Biological Process		9
GO:0030282	bone mineralization	Biological Process		5
GO:0042470	melanosome	Cellular Component		22
GO:0008285	negative regulation of cell proliferation	Biological Process	TAS[7814155]	59
GO:0016021	integral to membrane	Cellular Component	TAS[7814155]	845

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GPNMB (count: 0)

Genes shared at least 2 KEGG pathways with GPNMB (count: 0)

View in gBrowse

Region: chr7:23275586..23314729 View in gBrowse