ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FTO
Symbol Alias	KIAA1752, MGC5149
Approved Name	fat mass and obesity associated
Location	16q12.2
Position	chr16:53737875-54155853, +
External Links	HGNC: 24678 Entrez Gene: 79068 Ensembl: ENSG00000140718 UCSC: uc002ehr.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_175	chr16:52617706-52880769 (NCBI Build 35 (hg17))	263064	16q12.2	Duplication	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0035552	oxidative single-stranded DNA demethylation	Biological Process	IDA[18775698]	1
GO:0035553	oxidative single-stranded RNA demethylation	Biological Process	IDA[18775698]	2
GO:0035515	oxidative RNA demethylase activity	Molecular Function	IDA[18775698]	2
GO:0035516	oxidative DNA demethylase activity	Molecular Function	IDA[18775698]	1
GO:0010883	regulation of lipid storage	Biological Process		1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Molecular Function		11
GO:0006307	DNA dealkylation involved in DNA repair	Biological Process	IDA[18775698]	1
GO:0008198	ferrous iron binding	Molecular Function		5
GO:0070989	oxidative demethylation	Biological Process	IDA[18775698]	1
GO:0080111	DNA demethylation	Biological Process	IDA[18775698]	1
GO:0060612	adipose tissue development	Biological Process		7
GO:0070350	regulation of white fat cell proliferation	Biological Process		1
GO:0043734	DNA-N1-methyladenine dioxygenase activity	Molecular Function		1
GO:0044065	regulation of respiratory system process	Biological Process		1
GO:0040014	regulation of multicellular organism growth	Biological Process		6
GO:0042245	RNA repair	Biological Process	IDA[18775698]	1
GO:0005634	nucleus	Cellular Component	ISS[17991826]	770
GO:0001659	temperature homeostasis	Biological Process		4

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FTO (count: 0)

Genes shared at least 2 KEGG pathways with FTO (count: 0)

View in gBrowse

Region: chr16:53737875..54155853 View in gBrowse